Publications by authors named "Margarita Strokova-Stoilova"
Article Synopsis
- Both peripheral neuropathy and depression associated with diabetes can result from sodium-calcium imbalance, prompting a study on the drug KB-R7943 as a potential treatment in a rat model.
- The pharmacokinetic study showed differences in drug exposure and distribution between diabetic rats and controls, with notable accumulation in the brain and heart, but lower penetration in diabetic rats.
- Chronic treatment with KB-R7943 demonstrated dose-dependent improvement in neuropathic and depression-like symptoms, indicating its potential for treating neurodegenerative effects of diabetes, although further safety studies are needed.
Background: Rotavirus (RV) causes a high proportion of acute gastroenteritis (AGE) cases, especially among children under the age of five years old. This surveillance study was undertaken to study the incidence and severity of rotavirus gastroenteritis (RVGE) in primary care settings in Bulgaria over a one-year period.
Methods: In this prospective, observational study of AGE cases in children under five years of age presenting in the primary care setting over a one year period, stool samples were collected and tested for RV using a rapid visual immunochromatographic test kit.