Ann Clin Microbiol Antimicrob
December 2018
Background: The widespread Escherichia coli clone ST131 implicated in multidrug-resistant infections has been recently reported, the majority belonging to O25:H4 serotype and classified into five main virotypes in accordance with the virulence genes carried.
Methods: Pathogenicity Islands I and II (PAI-I and PAI-II) were determined using conventional PCR protocols from a set of four E. coli CTX ST131 O25:H4/H30-Rx strains collected from healthy donors' stool.
Purpose: infections in hospitals constitute an important problem due to the increasing multidrug resistance (MDR) and carbapenems resistance. The knowledge of resistance mechanisms in strains is an important issue for an adequate antimicrobial treatment. Therefore, the objective was to investigate other antimicrobial resistance mechanisms in MDR strains carrying , make a partial plasmids characterization, and determine if modifications in gene affect the expression of the OprD protein.
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