Publications by authors named "Margarita Ignateva"

Article Synopsis
  • * In areas without universal mass vaccination (UMV), seroprevalence has shifted to older age groups, while regions with child vaccination programs saw significant increases in HERD immunity among younger populations.
  • * The findings indicate a need for national implementation of UMV, along with strategies to improve vaccination coverage and conduct catch-up campaigns to sustain the effectiveness of existing programs.
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Background: The geographic distribution of the hepatitis B virus (HBV) and the hepatitis D virus (HDV) genotypes is uneven. We reconstructed the temporal evolution of HBV and HDV in Yakutia, one of the regions of Russia most affected by HBV and HDV, in an attempt to understand the possible mechanisms that led to unusual for Russia pattern of viral genotypes and to identify current distribution trends.

Methods: HBV and HDV genotypes were determined in sera collected in 2018-2019 in Yakutia from randomly selected 140 patients with HBV monoinfection and 59 patients with HBV/HDV.

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Universal hepatitis B vaccination of newborns was implemented in Russia starting from 1998. From 1998 to 2019, the incidence of acute hepatitis B reduced from 43.8 to 0.

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Article Synopsis
  • Population growth, socio-cultural and economic changes, and technological advances are putting pressure on the environment, impacting ecosystems and human health.
  • Arctic regions, like the Republic of Sakha (Yakutia), are particularly affected by climate change, leading to thawing permafrost that alters habitats and increases the risk of zoonotic diseases.
  • A German-Russian Symposium held in Yakutsk assessed these challenges under the "One Health" concept, highlighting the connection between environmental health and human well-being.
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