Publications by authors named "Margarita Gelvez"
Article Synopsis
- A study in Colombia aimed to identify factors that predict mortality in dengue patients, highlighting the need for risk assessment and timely treatment to reduce fatalities in endemic regions.
- Researchers analyzed data from 110 fatal cases and 217 nonfatal controls, finding that certain symptoms like respiratory distress and jaundice significantly increased the risk of death, while symptoms like retro-ocular pain and nausea were less common in fatal cases.
- The findings suggest that recognizing severe dengue features can improve patient triage and management, potentially lowering the 98% preventable mortality rate emphasized by the World Health Organization.
Introduction: Dengue is currently among the mosquito-borne diseases of greatest global impact. The clinical course of the disease can be unpredictable, so proper handling in its early stages is critical to ensure optimal outcomes.
Objective: To evaluate serum regulators of endothelial integrity (VEGF, sICAM-1, sEndoglina, Ang-1, and Ang-2) as predictive markers of dengue severity.
Objectives: Dengue represents the most important arboviral infection worldwide. Onset of circulatory collapse can be unpredictable. Biomarkers that can identify individuals at risk of plasma leakage may facilitate better triage and clinical management.
View Article and Find Full Text PDFBackground: Dengue fever and leptospirosis have partially overlapping geographic distributions, similar clinical presentations and potentially life-threatening complications but require different treatments. Distinguishing between these cosmopolitan emerging pathogens represents a diagnostic dilemma of global importance. We hypothesized that perturbations in host biomarkers can differentiate between individuals with dengue fever and leptospirosis during the acute phase of illness.
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