Publications by authors named "Margarita Cano"
Article Synopsis
- Dairy cattle breeds face recurrent recessive genetic defects that are often undetected due to conventional observation techniques missing various conditions, particularly those without clear symptoms.
- A new data mining framework has been developed to identify these hidden recessive defects in livestock by analyzing genomic data and comparing homozygote numbers in cattle with diverse life histories.
- This research uncovered 33 new genetic loci linked to increased juvenile mortality, offering insights into the genetic causes of inbreeding depression, which can enhance animal welfare and reduce industry losses.
Substance use disorders (SUD) treatment centers are an optimal setting for delivering smoking cessation interventions (SCI). This study aimed to examine the adoption of SCI in SUD treatment centers in Catalonia (Spain) as well as to assess their managers' views on the appropriateness and feasibility of providing SCI. Managers directly in charge of SUD treatment centers (n = 57) answered a 30-item on-line questionnaire.
View Article and Find Full Text PDFBackground: In mammals, hypohidrotic ectodermal dysplasia (HED) is a genetic disorder that is characterized by sparse hair, tooth abnormalities, and defects in cutaneous glands. Only four genes, EDA, EDAR, EDARADD and WNT10A account for more than 90% of HED cases, and EDA, on chromosome X, is involved in 50% of the cases. In this study, we explored an isolated case of a female Holstein calf with symptoms similar to HED.
View Article and Find Full Text PDFThe composition and structure of fleece variation observed in mammals is a consequence of a strong selective pressure for fiber production after domestication. In sheep, fleece variation discriminates ancestral species carrying a long and hairy fleece from modern domestic sheep (Ovis aries) owning a short and woolly fleece. Here, we report that the "woolly" allele results from the insertion of an antisense EIF2S2 retrogene (called asEIF2S2) into the 3' UTR of the IRF2BP2 gene leading to an abnormal IRF2BP2 transcript.
View Article and Find Full Text PDFUnlabelled: The safety of varenicline in the treatment of tobacco dependence has been questioned, in psychiatric patients. However, most published studies have not included psychiatric patients.
Objective: Assess the safety of varenicline for smoking cessation in patients with psychiatric disorders.