Publications by authors named "Margarida Celia Lima Costa Neves"

Unlabelled: The progression of chronic obstructive pulmonary disease (COPD) is characterized by functional changes in the airways. The lung-gut axis and gut microbiota (GM) have been linked to the pathophysiology of airway diseases. Regarding COPD, studies have shown that GM alterations could be related the stages of this disease.

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: Chronic Obstructive Pulmonary Disease (COPD) is a disease of premature aging, characterized by airflow limitations in the lungs and systemic chronic inflammation. This systematic review aimed to provide a systematic overview of immunosenescence and inflammation in Chronic Obstructive Pulmonary Disease (COPD). The PubMed, Science Direct, Scopus, Cochrane Library, and Web of Science databases were searched for studies on markers of immunosenescence.

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Chronic Obstructive Pulmonary Disease (COPD) is a disease of the lungs characterized by chronic airflow obstruction. Individuals with preserved ratio impaired spirometry (PRISm) may be at risk for developing COPD. This study aimed to characterize PRISm and COPD patients in terms of their immune response and endocrine profile to identify differences extending beyond lung function.

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Objective:: To determine whether COPD severity correlates with sputum cell counts, atopy, and asthma.

Methods:: This was a cross-sectional study involving 37 patients with COPD and 22 healthy subjects with normal lung function (controls). Sputum cell counts were determined by microscopy after centrifugation of samples.

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Article Synopsis
  • The study aimed to assess how common atopy is in patients with Chronic Obstructive Pulmonary Disease (COPD) and to analyze their clinical and lab profiles.
  • 149 outpatients with stable COPD participated, providing information through questionnaires and undergoing various medical tests like skin prick tests and nasal lavage cytology.
  • Findings showed a significant portion of these patients exhibited signs of atopy, highlighting a connection between nasal inflammation and respiratory function, suggesting that monitoring upper airway inflammation could aid in understanding respiratory issues, particularly in older patients with both asthma and COPD.
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