Publications by authors named "Margarete van der Meer"
Article Synopsis
- - Cu(II) complexes were created using cyclen-based ligands that include different types of donor atoms like sulfur (S) and oxygen (O), with the aim of improving DNA cleavage activity.
- - The study found that replacing nitrogen (N) donor atoms with hard O donors made the complexes efficient at cleaving DNA but unstable upon reduction, prompting researchers to try S donors instead for stability.
- - By smartly combining O and S with nitrogen in the cyclic structure, the researchers designed a new complex that maintains both its oxidized and reduced forms, resulting in the best DNA cleavage activity without losing copper during the process.
