Medical treatment of miscarriage in a district general hospital is safe and effective up to 12 weeks' gestation.

The findings are reported of a retrospective study of 207 women undergoing medical evacuation of the uterus for first trimester miscarriage, using mifepristone followed by a single dose of oral misoprostol. All women had the diagnosis confirmed by ultrasonography. Complete medical evacuation was achieved in 88% of cases.

Mifepristone and misoprostol for medical termination of pregnancy: the effectiveness of a flexible regimen.

Background: Mifepristone, followed 48 hours later by administration of misoprostol, is a well-established regimen for medical termination of pregnancy (TOP). Although this regimen is effective, its inflexibility may limit its provision in an outpatient service.

Objective: To confirm that misoprostol administration is effective whether administered 24, 48 or 72 hours after oral mifepristone.