Rituximab for Treatment of Refractory Anti-NMDA Receptor Encephalitis in a Pediatric Patient.

Anti--methyl d-aspartate receptor (anti-NMDAR) encephalitis is a devastating disease that is increasingly being identified in both children and adults with psychosis, language disturbances, behavioral changes, and motor deficits. Currently no consensus guidelines exist for the optimal management of patients with this disease, although intravenous immune globulin (IVIG) therapy is often considered first-line pharmacotherapy. We present a case of an otherwise healthy 4 year-old-child who presented with seizures, loss of age-appropriate language skills, and behavioral changes, in whom anti-NMDAR was subsequently diagnosed.

Impact of socioeconomic deprivation on maternal perinatal mental illnesses presenting to UK general practice.

Background: Although maternal perinatal mental illnesses commonly present to and are primarily treated in general practice, few population-based estimates of this burden exist, and the most affected socioeconomic groups of pregnant women remain unclear.

Aim: To provide estimates of maternal depression, anxiety and serious mental illness (SMI) in UK general practice and quantify impacts of socioeconomic deprivation.

Design And Setting: Cross-sectional analysis of prospectively recorded general practice records from a UK-wide database.

Saving Mothers' Lives: Reviewing maternal deaths to make motherhood safer: 2006-2008. The Eighth Report of the Confidential Enquiries into Maternal Deaths in the United Kingdom.

In the triennium 2006-2008, 261 women in the UK died directly or indirectly related to pregnancy. The overall maternal mortality rate was 11.39 per 100,000 maternities.

Invited commentaries on... Abortion and mental health disorders.

The finding that induced abortion is a risk factor for subsequent psychiatric disorder in some women raises important clinical and training issues for psychiatrists. It also highlights the necessity for developing evidence-based interventions for these women. P.

Maternal self-esteem after successful treatment for infertility.

Objective: To [1] investigate self-esteem during pregnancy after previous infertility and [2] establish the relationship among self-esteem, anxiety during pregnancy, and parenting self-efficacy.

Design: Limited prospective study.

Setting: A regional infertility clinic and antenatal clinic.

Parenting stress in first-time mothers of twins and triplets conceived after in vitro fertilization.

Objective: To examine psychosocial and obstetric outcomes at 1 year postpartum in first-time mothers who conceived after IVF.

Design: Prospective cohort study.

Setting: University medical center in the United Kingdom.