Publications by authors named "Margaret M Albanese"
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Synopsis of recent research by authors named "Margaret M Albanese"
- Margaret M Albanese's research primarily focuses on the development and optimization of histamine H3 receptor antagonists, which have potential therapeutic benefits in treating various neurological and psychiatric disorders.
- Her studies outline the synthesis of novel compounds, such as the 4-benzimidazolyl-piperidinylcarbonyl-piperidine and 4-benzyl-(1H-imidazol-4-yl) templates, demonstrating significant improvements in receptor selectivity and oral bioavailability.
- Albanese's work also addresses the issue of CYP450 enzyme inhibition in her compounds, highlighting structural modifications that mitigate this common side effect, thus enhancing their clinical viability.
