Wastewater-based analysis of antimicrobial resistance at UK airports: Evaluating the potential opportunities and challenges.

With 40 million annual passenger flights, airports are key hubs for microbial communities from diverse geographic origins to converge, mix, and distribute. Wastewater derived from airports and aircraft represent both a potential route for the global dispersion of antimicrobial resistant (AMR) organisms and an under-utilised resource for strengthening global AMR surveillance. This study investigates the abundance and diversity of antimicrobial resistance genes (ARGs) in wastewater samples collected from airport terminals (n = 132), aircraft (n = 25), and a connected wastewater treatment plant (n = 11) at three international airports in the UK (London Heathrow, Edinburgh and Bristol).

The Impact of an Online Educational Intervention on Attitudes of Primary Care Clinicians Toward Managing Patients With Substance Use Disorders.

Background: Negative attitudes of primary care clinicians toward patients with substance use disorders affect the quality and delivery of care in this highly marginalized patient population.

Purpose: This project aimed to improve negative attitudes of primary care clinicians toward managing patients with substance use disorders.

Methods: A pretest-and-posttest design, employing multidimensional online educational interventions, was implemented from June to August 2020.

A Case Study on the Practical Use of Low-Fidelity Modeling to Mitigate the Spread of COVID-19 Amongst the Underserved Farmworker Community.

In March of 2020, with the full magnitude of the COVID-19 pandemic yet to be seen, Costa and Martin released a report through the Economic Policy Institute noting that "To prevent infections and the spread of COVID-19 on farms, farm employers should be planning and implementing safety measures to protect their employees" (Costa D, Martin P, Coronavirus and farmworkers: farm employment, safety issues, and the H-2A guestworker program, Economic Policy Institute, https://www.epi.org/publication/coronavirus-and-farmworkers-h-2a/, 2020).

Safety and effectiveness of resistance training in patients with late onset Pompe disease - a pilot study.

Pompe disease is a progressive myopathy resulting from deficiency in lysosomal enzyme acid α-glucosidase (GAA), which leads to glycogen accumulation in lysosomes primarily in skeletal and cardiac muscle. Enzyme replacement therapy (ERT) with recombinant human (rh) GAA works well in alleviating the cardiomyopathy; however, many patients continue to have progressive muscle weakness. The purpose of this study was to evaluate the effectiveness of a respiratory training combined with 24-week supervised resistance training program on muscle strength (measured by Biodex)), and respiratory function including maximum inspiratory pressure (MIP), maximum expiratory pressure (MEP) in subjects with late onset Pompe disease receiving ERT.

Machine learning-based outcome prediction and novel hypotheses generation for substance use disorder treatment.

Objective: Substance use disorder is a critical public health issue. Discovering the synergies among factors impacting treatment program success can help governments and treatment facilities develop effective policies. In this work, we propose a novel data analytics approach using machine learning models to discover interaction effects that might be neglected by traditional hypothesis-generating approaches.

Variable clinical features of patients with Fabry disease and outcome of enzyme replacement therapy.

Fabry disease (FD) is an X-linked lysosomal storage disorder caused by a deficiency in the enzyme α-galactosidase A due to mutations in the gene. This leads to an accumulation of globotriaosylceramide (GL-3) in many tissues, which results in progressive damage to the kidneys, heart, and nervous system. We present the molecular and clinical characteristics and long-term outcomes of FD patients from a multidisciplinary clinic at the University of California, Irvine treated with agalsidase beta enzyme replacement therapy (ERT) for 2-20 years.

Co-culture with Synechococcus facilitates growth of Prochlorococcus under ocean acidification conditions.

Anthropogenic CO emissions are projected to lower the pH of the ocean 0.3 units by 2100. Previous studies suggested that Prochlorococcus and Synechococcus, the numerically dominant phytoplankton in the oceans, have different responses to elevated CO that may result in a dramatic shift in their relative abundances in future oceans.

Educational and learning morbidity in pediatric heart transplant recipients: A pediatric heart transplant society study.

Educational development is an important component of quality of life for children with heart transplant. Aims include determining prevalence of and risk factors for modified education placement in a large representative sample of pediatric heart transplant recipients. Participants included 1495 patients (age 6-18 years) from the PHTS database.

Accelerometers: Assessing their potential for measuring personal flotation device use on commercial fishing vessels.

Background: Falls overboard are the most common cause of fatalities in commercial fishing. As a result, interventions aimed at increasing and measuring the use of personal flotation devices (PFDs) are a high priority. The focus of this study was to explore the use of accelerometers as a means for objectively measuring PFD use on lobster fishing vessels.

Genetic aetiologies should be considered in paediatric cases of acute heart failure presumed to be myocarditis.

There are a variety of causes of acute heart failure in children including myocarditis, genetic/metabolic conditions, and congenital heart defects. In cases with a structurally normal heart and a negative personal and family history, myocarditis is often presumed to be the cause, but we hypothesise that genetic disorders contribute to a significant portion of these cases. We reviewed our cases of children who presented with acute heart failure and underwent genetic testing from 2008 to 2017.

Validating the Secondary Traumatic Stress Scale for Pediatric Nurses.

Background And Purpose: Secondary traumatic stress is a state of mental distress resulting from indirect exposure to the traumatic situation of another individual. The literature indicates that secondary traumatic stress is a problem in some areas of nursing and may cause nurses to leave the profession. This article examines the psychometrics of the Secondary Traumatic Stress Scale (STSS) with a sample of pediatric nurses.

Secondary Traumatic Stress in Pediatric Nurses.

Purpose: Secondary traumatic stress affects many in the helping professions, and has been identified in many nursing specialty areas. The purpose of this study was to expand the knowledge of secondary traumatic stress in pediatric nursing by examining the statistical relationships between secondary traumatic stress, age of the nurse, and years of nursing experience, and coping responses.

Design And Methods: A convenience sample of Certified Pediatric Nurses (n = 338) were surveyed using the Secondary Traumatic Stress Scale, the Brief COPE, the Marlowe-Crowne Social Desirability-Short Form, and a demographics form.

Providing Physical Care to Persons With Serious Mental Illness: Attitudes, Confidence, Barriers and Psychological Empowerment.

The prevalence of metabolic syndrome (MetS) in people with serious mental illness (SMI) has been well documented in the mental health literature. Despite the adoption of various guidelines for monitoring risk factors for diabetes and cardiovascular risk in this population, limited translation has occurred in actual practice (Hermes, Sernyak, & Rosenheck, 2013). The Institute of Medicine (IoM) (2009) has noted a lag time in the application of knowledge within clinical settings.

Diagnostic Errors: Impact of an Educational Intervention on Pediatric Primary Care.

Introduction: The purpose of our study was to determine the impact of an educational program on a provider's knowledge related to diagnostic errors and diagnostic reasoning strategies.

Methods: A quasi-experimental interventional study with a multimedia approach, case study discussion, and trigger-generated medical record review at two time points was conducted. Measurement tools included a test developed by the National Patient Safety Foundation, Reducing Diagnostic Errors: Strategies for Solutions Quiz, additional diagnostic reasoning questions, and a trigger-generated process to analyze medical records.

Metabolic Syndrome: Psychiatric-Mental Health Nurses' Knowledge of Risks and Care Practices.

Comorbidity of serious mental illness (SMI) and metabolic syndrome contributes to the reduced lifespan of individuals with SMI. Integration of physical and mental health care has been slow. The current study explored the level of knowledge of metabolic syndrome and practices of psychiatric-mental health nurses related to metabolic syndrome risks.

Sustained Isoprostane E2 Elevation, Inflammation and Fibrosis after Acute Ischaemia-Reperfusion Injury Are Reduced by Pregnane X Receptor Activation.

Liver grafts donated after cardiac death are increasingly used to expand the donor pool but are prone to ischaemic-type biliary lesions. The anti-inflammatory effects of the activated pregnane X receptor have previously been shown to be beneficial in a number of inflammatory liver conditions. However, its role in reducing peri-portal inflammation and fibrosis following ischaemia-reperfusion injury has not been investigated.

Nursing Care for Lifestyle Behavioral Change.

The purpose of this pilot study was to determine if metabolic risk factors can be stabilized or improved with weekly motivational interviewing/coaching and medical follow-up care focused on lifestyle behavioral change in individuals with serious mental illness. Individuals were followed for 18 weeks following discharge from an inpatient psychiatric service. All individuals were prescribed an antipsychotic medication and had at least two risk factors for metabolic syndrome.

The effect of hospital organizational characteristics on postoperative complications.

Objectives: To determine if there is a relationship between the risk of postoperative complications and the nonclinical hospital characteristics of bed size, ownership structure, relative urbanicity, regional location, teaching status, and area income status.

Methods: This study involved a secondary analysis of 2006 administrative hospital data from a number of U.S.

A qualitative analysis of orthodontic-related posts on Twitter.

Objective: To investigate the content of orthodontic-related Twitter posts in order to improve our understanding of orthodontic patients' perceptions and treatment experiences.

Materials And Methods: Some 131 consecutive posts were collected from Twitter over a 5-day period. Twitter's advanced-search function was used to limit the sampling frame to New Zealand.

Data synthesis in community health assessment: practical examples from the field.

State and local health departments (LHDs) are increasingly conducting community health assessments, using models such as Mobilizing for Action through Planning and Partnerships. Within the peer-reviewed literature, relevant Web sites, and textbooks on health planning, there is limited practical guidance for bridging data collection and prioritization. The purpose of this article was to provide examples of how LHDs have bridged these steps through "data synthesis.

Making healthy connections: introducing nursing as a career choice to middle school students.

The current economic climate has resulted in many experienced nurses returning to the workforce. Despite this, the nursing shortage is looming in our future and the recruitment of a diverse nursing workforce reflective of the population remains a high priority. The Merrimack Valley in northeastern Massachusetts has two large cities, Lawrence and Lowell, in which the Hispanic and the Southeast Asian populations are disproportionately higher than state and national levels.

Access to mental health care among older adults.

Many older adults experience common mental health problems that can have a negative impact on physiological health, functional status, and quality of life. Lack of access to mental health care for community-dwelling older adults is a significant problem. Busy primary care practices, few mental health professionals, inadequate problem recognition, and flaws in the health care system all contribute to restricted access to mental health care.

Models for local implementation of comprehensive cancer control: meeting local cancer control needs through community collaboration.

The comprehensive cancer control approach is used by state, tribes, tribal organizations, territorial and Pacific Island Jurisdiction cancer coalitions to spur local implementation of cancer plans to reduce the burden of cancer in jurisdictions across the country. There is a rich diversity of models and approaches to the development of relationships and scope of planning for cancer control activities between coalitions and advocates in local communities. The national comprehensive cancer control philosophy provides an operational framework while support from the Centers for Disease Control and Prevention enables coalitions to act as catalysts to bring local partners together to combat cancer in communities.