Publications by authors named "Margaret J McGill"
Article Synopsis
- Diabetes in young adults can be difficult to classify, particularly when involving diabetic ketoacidosis (DKA) seen in both type 1 and type 2 diabetes, and can also be linked to rare conditions like Beta-ketothiolase deficiency (BKD).
- A novel case is presented of a 34-year-old man with BKD who experienced DKA, which is unique because previous reports haven't documented diabetes in adults with BKD.
- The findings stress the need for regular HbA1c checks in those with BKD and raised blood sugar levels to identify possible concurrent diabetes, which can help avoid complications and improve treatment strategies.
Circulating soluble CD163 as a potential biomarker of diabetes complications.
J Diabetes Complications
August 2023
Aims: To investigate whether soluble CD163 (sCD163) is altered in those with diabetes and various subtypes of complications and non-alcoholic fatty liver disease (NAFLD), and whether it can assess disease complications and severity in people with diabetes.
Methods: Adults with diabetes (n = 101) were recruited and assessed for the presence of any complications (D). Liver steatosis presence was determined by ultrasound and liver stiffness measurement (LSM) by transient elastography.
Glucose monitoring has evolved from self-monitoring of blood glucose to glycated hemoglobin, and the latest continuous glucose monitoring (CGM). A key challenge to adoption of CGM for management of diabetes in Asia is the lack of regional CGM recommendations. Hence, thirteen diabetes-specialists from eight Asia-Pacific (APAC) countries/regions convened to formulate evidence-based, APAC-specific CGM recommendations for individuals with diabetes.
View Article and Find Full Text PDFIntroduction: Type 2 diabetes in young adults (nominally, 18-30 years of age) is a more aggressive condition than that seen in older age, with a greater risk of major morbidity and early mortality. This first Australian consensus statement on the management of type 2 diabetes in young adults considers areas where existing type 2 diabetes guidance, directed mainly towards older adults, may not be appropriate or relevant for the young adult population. Where applicable, recommendations are harmonised with current national guidance for type 2 diabetes in children and adolescents (aged < 18 years).
View Article and Find Full Text PDFObjective: To study the effect of 12 weeks of high-intensity interval training (HIIT) on glycemic control in adults with type 1 diabetes and overweight or obesity.
Research Design And Methods: Thirty inactive adults with type 1 diabetes who had BMI ≥25 kg/m and HbA ≥7.5% were randomized to 12 weeks of either HIIT exercise intervention consisting of 4 × 4-min HIIT (85-95% peak heart rate) performed thrice weekly or usual care control.
Objective: Hypoglycaemia related to exercise and lack of confidence to exercise, are common in T1DM. An online educational exercise tool (ExT1D) was tested to determine whether these parameters can be improved.
Research Design And Methods: Thirty two adults with T1DM (50%M, age 35.