Publications by authors named "Margaret I Arbuckle"
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Synopsis of recent research by authors named "Margaret I Arbuckle"
Margaret I Arbuckle's research primarily focuses on the role of postsynaptic density protein 95 (PSD-95) in various aspects of neuronal function, particularly in relation to pain modulation and synaptic plasticity associated with psychiatric disorders.
Her studies have identified PSD-95 as a critical mediator for the actions of hallucinogens and atypical antipsychotic drugs at serotonin receptors, highlighting its importance in both neurotransmission and the modulation of behavior.
Arbuckle's investigations also reveal genetic links to psychiatric illnesses such as bipolar disorder, implying that genetic components play a significant role in these complex disorders, which could inform future therapeutic approaches.
