The impact of LH-containing gonadotropins on diploidy rates in preimplantation embryos: long protocol stimulation.

Background: The aim of this study was to evaluate the effect of ovarian stimulation with LH-containing gonadotropins (human menopausal gonadotropin, hMG), on ploidy of human cleavage-stage-embryos.

Methods: A total of 104 women, at ages 27-43 years, undergoing one cycle of controlled ovarian hyperstimulation for IVF in combination with preimplantation genetic diagnosis, were eligible for enrollment in this retrospective, controlled cohort study. Ovarian stimulation included down-regulation with long agonist and stimulation with either recombinant FSH or hMG.

Patterns of ovarian response to gonadotropin stimulation in female carriers of balanced translocation.

Objective: To determine whether maternal balanced translocation is a risk factor for poor ovarian response to controlled ovarian hyperstimulation (COH).

Design: A retrospective analysis.

Setting: Private IVF center.