Publications by authors named "Margaret E Greer"
Article Synopsis
- * A bibliometric analysis from 2008 to 2023 showed fluctuations in female authorship, with a peak in 2011 followed by declines and a more recent rebound by 2023.
- * Despite an overall increase in female authorship, significant disparities still exist in senior roles, highlighting the need for stronger policies to support women's advancement in IR.
Bimekizumab-bkzx for the Treatment of Plaque Psoriasis: A Drug Review.
Ann Pharmacother
October 2024
Background: Bimekizumab is a biologic targeting interleukin (IL)-17A/17F, approved by the Food and Drug Administration (FDA) for moderate-to-severe plaque psoriasis in 2023.
Data Sources: A PubMed search was performed using the keywords "bimekizumab," "plaque psoriasis," and "bimekizumab clinical trials," from origin to August 1, 2024. We included phase I to III trials of bimekizumab for plaque psoriasis, studies published post-FDA approval, and information from the package insert.
Article Synopsis
- Medical-legal partnerships (MLPs) aim to address health inequities by combining the efforts of legal and health professionals to tackle the legal factors affecting patients' health.
- While past research on MLPs has mainly focused on individual benefits for patients and systems, there's a call for future studies to explore the impact on community empowerment as a critical process in building equity.
- The article emphasizes the importance of assessing how MLPs can help shift power to affected communities, allowing them to set and lead health equity initiatives.
The immunomodulatory imide drug (IMiD) class, which includes the founding drug member thalidomide and later generation drugs, lenalidomide and pomalidomide, has dramatically improved the clinical treatment of specific cancers, such as multiple myeloma, and it combines potent anticancer and anti-inflammatory actions. These actions, in large part, are mediated by IMiD binding to the human protein cereblon that forms a critical component of the E3 ubiquitin ligase complex. This complex ubiquitinates and thereby regulates the levels of multiple endogenous proteins.
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