6-n-Propylthiouracil sensitivity and obesity status among ethnically diverse children.

Objective: To examine the relationship of 6-n-propylthiouracil (PROP) sensitivity to BMI while statistically controlling for demographic characteristics in two age groups of children: 9-10 years and 17-18 years (n 1551).

Design: Cross-sectional design with a multi-ethnic (White, African-American, Hispanic, Other) sample of 813 children aged 9-10 years and 738 children aged 17-18 years. Children were recruited from local elementary and high schools with at least 30 % minority ethnic enrolment.

Gene-nutrition interaction in human performance and exercise response.

Recent advances in human performance research have revealed new insight into the many factors that influence how an individual responds to exercise training. Response to exercise interventions is often highly variable among individuals, however, and exercise response may be mediated in large part by variation in genes and nutrition and by gene-environment interactions. It is well established that the quality and quantity of nutritional intake play a critical role in response to training and in athletic performance.