Publications by authors named "Margaret B Nagel"

Article Synopsis
  • The study looked at using higher doses of radiation therapy (RT) for kids and young adults with big tumors from Ewing sarcoma (EWS) to see if it helps control the cancer better.
  • They treated patients with tumors 8 cm or larger using special types of radiation and found that most of them had good results over 5 years, with a 64.2% chance of surviving.
  • Although many patients had side effects from the treatment, most were not very serious, showing that the higher doses of radiation might be safe and effective.
View Article and Find Full Text PDF
Article Synopsis
  • A study was conducted on 38 children and young adults with melanocytic lesions to investigate genetic variants linked to cancer at St. Jude Children's Research Hospital.
  • The group included patients with various types of melanoma, including malignant melanoma, spitzoid melanoma, and uveal melanoma.
  • About 15.8% of the patients were found to carry pathogenic germline variants associated with cancer, including notable genes like TP53, BRIP1, and ATM.
View Article and Find Full Text PDF