Publications by authors named "Maren Webster"

Untreated infective endocarditis (IE) is uniformly fatal. The practice of combination antibiotic therapy for IE is recommended by treatment guidelines but largely unsupported by high-quality evidence. This study aimed to assess the efficacy of combination antibiotic therapy compared to monotherapy in IE through a systematic review and meta-analysis.

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Article Synopsis
  • Staphylococcus aureus is a major cause of bacterial bloodstream infections, and there is conflicting evidence about whether female patients have a higher mortality risk compared to males.
  • This study aimed to clarify the relationship between female sex and mortality in patients with Staphylococcus aureus bacteremia (SAB) by analyzing data from various research sources.
  • The findings indicated that female patients had a statistically significant higher risk of mortality both in unadjusted and adjusted analyses, supporting the notion that female sex is a risk factor for increased mortality in SAB cases.
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Objectives: The association of biological female sex with outcome in patients with Staphylococcus aureus bacteraemia remains unresolved. The aim of this study was to determine the independent association of female sex with management and mortality in patients with S. aureus bacteraemia.

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