Tricenter analysis of cofactors and comorbidity in patients with pyoderma gangrenosum.

Introduction: Pyoderma gangrenosum (PG) is a rare neutrophilic, ulcerative skin disease of largely unknown pathophysiology.

Material And Methods: In this study, potentially relevant cofactors and comorbidities in patients with PG from three dermatological wound care centers in Germany were evaluated.

Results: Of the 121 patients assessed, women (66.

Trizentrische Analyse von Kofaktoren und Komorbidität des Pyoderma gangraenosum.

Einleitung: Das Pyoderma gangraenosum (PG) ist eine seltene, inflammatorische destruktiv-ulzerierende neutrophile Erkrankung mit weitgehend unklarer Pathophysiologie.

Material Und Methodik: In dieser Studie wurden die potenziell relevanten Kofaktoren und Begleiterkrankungen von Patienten mit PG aus drei dermatologischen Wundzentren in Deutschland differenziert ausgewertet.

Ergebnisse: Von den insgesamt 121 analysierten Patienten waren Frauen (66,9 %) häufiger betroffen als Männer.

Bacterial spectrum colonizing chronic leg ulcers: a 10-year comparison from a German wound care center.

Background And Objectives: Chronic wounds are colonized by many different bacteria.

Patients And Methods: We analyzed microbiological swabs from chronic leg ulcers from 2012/2013 and matched the results with those from 2002/2003 and 2007/2008 from the same institution.

Results: Results from 100 patients from our specialized wound care center were evaluated retrospectively.

A novel epidermal growth factor--containing wound dressing for the treatment of hard-to-heal venous leg ulcers.

Objective: To evaluate the efficacy, tolerability, and safety of a novel wound dressing containing epidermal growth factor (EGF) in a collagen-gel matrix on hard-to-heal venous leg ulcers.

Patients And Methods: The authors included 33 hard-to-heal venous leg ulcers found on 31 patients. The EGF-containing dressing was applied 3 times while best practice conservative wound treatment was continued.

Ulcerated necrobiosis lipoidica as a rare cause for chronic leg ulcers: case report series of ten patients.

Necrobiosis lipoidica is a rare granulomatous disorder of the skin. In up to 30% of the affected patients it can lead to ulcerations, which can impair the quality of life and are also very difficult to treat. Its pathogenesis is not fully understood.