Publications by authors named "Marella R Verde"
Renal and Vascular Functional Decline in Aged Low Birth Weight Murine Adults.
Kidney Blood Press Res
December 2024
Article Synopsis
- Maternal undernutrition leads to low birth weight in neonates, which can increase the risk for high blood pressure and kidney disease later in life, though the exact reasons are not fully understood.
- The study utilized a mouse model to examine factors like oxidative stress and vascular function in low birth weight mice after one year, measuring various health indicators and testing different pharmacological treatments.
- Results showed that low birth weight mice had higher blood pressure and decreased kidney function, but administration of specific drugs improved their conditions, indicating that therapies targeting oxidative stress and vascular function might mitigate some long-term health issues.