MEETING HIGHLIGHTS: THE THIRD MARIE SKŁODOWSKA-CURIE SYMPOSIUM ON CANCER RESEARCH AND CARE AT ROSWELL PARK COMPREHENSIVE CANCER CENTER, BUFFALO, NY, SEPTEMBER 20-22, 2023.

Marie Skłodowska-Curie Symposia on Cancer Research and Care (MSCS-CRC) promote collaborations between cancer researchers and care providers in the United States, Canada and Central and Eastern European Countries (CEEC), to accelerate the development of new cancer therapies, advance early detection and prevention, increase cancer awareness, and improve cancer care and the quality of life of patients and their families. The third edition of MSCS-CRC, held at Roswell Park Comprehensive Cancer Center, Buffalo, NY, in September 2023, brought together 137 participants from 20 academic institutions in the US, Poland, Ukraine, Lithuania, Croatia and Hungary, together with 16 biotech and pharma entities. The key areas of collaborative opportunity identified during the meeting are a) creating of a database of available collaborative projects in the areas of early-phase clinical trials, preclinical development, and identification of early biomarkers; b) promoting awareness of cancer risks and efforts at cancer prevention; c) laboratory and clinical training; and d) sharing experience in cost-effective delivery of cancer care and improving the quality of life of cancer patients and their families.

Sensitivity Analysis of Determining the Material Parameters of an Asphalt Pavement to Measurement Errors in Backcalculations.

Nondestructive tests of road pavements are among the most widely used methods of pavement condition diagnostics. Deflections of road pavement under a known load are most commonly measured in such tests, e.g.

High Entrainment Constrains Synaptic Depression Levels of an Globular Bushy Cell Model.

Globular bushy cells (GBCs) located in the ventral cochlear nucleus are an essential part of the sound localization pathway in the mammalian auditory system. They receive inputs directly from the auditory nerve and are particularly sensitive to temporal cues due to their synaptic and membrane specializations. GBCs act as coincidence detectors for incoming spikes through large synapses-endbulbs of Held-which connect to their soma.

[Polonia Medyczna: struktura, współczesność i przyszłość].

It is estimated that approximately 20-25 000 polish physicians practice medicine in different countries outside of Poland, enriching medical workforces in their newly elected countries. The composition of this group, known as "Medical Polonia", has been changing from post Second World War emigration, resulting from the war and its political consequences, thru the next large wave of physicians leaving the communist country in 1980's. The last large group of Polish physicians has taken advantage of training opportunities or have started practices in the European Union, having departed Poland permanently or temporarily, after the country joined the European Union in 2004.

Expected and Unexpected Consequences of the Affordable Care Act: The Impact on Patients and Surgeons-Pro and Con Arguments.

The Patient Protection and Affordable Care Act (PPACA), called the Affordable Care Act (ACA) or "ObamaCare" for short, was enacted in 2010. The Public Policy and Advocacy Committee of the Society for Surgery of the Alimentary Tract (SSAT) hosted a debate with an expert panel to discuss the ACA and its impact on surgical care after the first year of patient enrollment. The purpose of this debate was to focus on the impact of ACA on the public and surgeons.

Modeling auditory coding: from sound to spikes.

Models are valuable tools to assess how deeply we understand complex systems: only if we are able to replicate the output of a system based on the function of its subcomponents can we assume that we have probably grasped its principles of operation. On the other hand, discrepancies between model results and measurements reveal gaps in our current knowledge, which can in turn be targeted by matched experiments. Models of the auditory periphery have improved greatly during the last decades, and account for many phenomena observed in experiments.

Robotic versus laparoscopic cholecystectomy inpatient analysis: does the end justify the means?

Background And Objectives: Robotic-assisted cholecystectomy (RAC) was introduced several years ago. With its more extensive use by surgeons, more information is needed regarding clinical and economic outcomes.

Methods: The Nationwide Inpatient Sample from the Health Cost Utilization Project was analyzed using HCUPnet, National Inpatient Sample (NIS) datasets and SAS 9.

Staying alive: strategies for accountable health care.

The Patient Protection and Affordable Care Act signed into law in March 2010, has led to sweeping changes to the US health care system. The ensuing pace of change in health care regulation is unparalleled and difficult for physicians to keep up with. Because of the extraordinary challenges that have arisen, the public policy committee of the Society for Surgery of the Alimentary tract conducted a symposium at their 52nd Annual Meeting in May 2011 to educate participants on the myriad of public policy changes occurring in order to best prepare them for their future.

A priori dietary omega-3 lipid supplementation results in local pancreatic macrophage and pulmonary inflammatory response attenuation in a model of experimental acute edematous pancreatitis (AEP).

Background: Acute pancreatitis is often complicated by multiorgan dysfunction, which is postulated to occur in part by macrophage infiltration into the pancreas. Eicosapentaenoic acid (EPA), an omega-3 fatty acid, is the principal biologic component of fish oil and has clinically and experimentally been demonstrated to be anti-inflammatory. We hypothesized that dietary EPA supplementation before the induction of pancreatitis would attenuate both M-mediated local pancreatic and systemic pulmonary inflammatory response in an in vivo model of acute edematous pancreatitis (AEP).