Publications by authors named "Marek Nora"
Article Synopsis
- The study investigates the impact of 3D-printed polycaprolactone (PCL) scaffolds with varying stiffness and porosity on bone tissue engineering and the immune response involved in bone regeneration.
- PCL scaffolds were produced using different techniques, revealing that high-temperature printing creates stiffer structures while low-temperature printing with NIPS results in more flexible, porous scaffolds.
- Results indicated that porosity and stiffness of the scaffolds influence not only the proliferation and mineralization of bone marrow-derived stem cells but also the activation of immune cells, suggesting a complex relationship between scaffold properties and biological responses.
Background: Chronic obstructive pulmonary disease (COPD) is a heterogeneous disease characterized by chronic bronchitis, emphysema and vascular remodelling. The disease is associated with hypoxia, inflammation and oxidative stress. Lung fibroblasts are important cells in remodelling processes in COPD, as main producers of extracellular matrix proteins but also in synthesis of growth factors and inflammatory mediators.
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