Publications by authors named "Marek Maczka"

Objectives: The objective of the paper is the suitability assessment of screening for Trisomy 18 and 13 on the basis of NT measurement, FHR, double test and assessment of Nasal Bone.

Material And Methods: The study was performed in 6,661 singleton pregnancies. In each fetus NT, FHR, DV-PIV were examined.

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Objectives: The aim of the study was to compare effects of addition of two methods of ductus venosus (DV) flow assessment: qualitative - the assessment of shape of the A-wave (positive or negative), and quantitative - based on the pulsatility index for veins (DVPI) to the basic screening for trisomy 21 at 11 to 13 + 6 weeks of pregnancy.

Material And Methods: The ultrasound examination was performed in 8230 fetuses in singleton pregnancies at 11- -13 + 6 wks, as a part of a routine screening for chromosomal defects. In DV A-wave was assessed and DVPI was calculated.

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Objectives: Trisomy 21 is one of the most common chromosomal defects diagnosed prenatally. Screening for Down syndrome is based on maternal age, measurement of crown-rump length, nuchal translucency and fetal heart rate, together with free β-hCG and PAPP-A at 11 to 13 + 6 weeks. Introduction of additional ultrasound marker of trisomy 21 (evaluation of the nasal bone) may result in increased DR and decreased invasive diagnostic testing rates (FPR).

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Article Synopsis
  • - The study aimed to compare the effectiveness of a combined screening test and an ultrasound-based method for detecting trisomy 18 (T18) in pregnant women, particularly looking at different cutoffs and age factors.
  • - Conducted with over 10,800 pregnancies, the findings showed that the ultrasound method had a 100% detection rate for T18, while the combined screening method had an 86% detection rate at a 3% false-positive rate.
  • - The results indicated that the ultrasound screening was more consistent across various maternal age groups, making it a preferable option over the combined screening method for T18 detection.
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Literature data about the effects of tobacco smoke constituents in pregnancy are reviewed. Analysis on the authors material comprises 73 smoking and 70 non-smoking women in pregnancy. In the former group the natal body weight of new born is by 308 g lower and the placental-fetal index by 0.

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Objectives: This paper presents a possibility of non-invasive diagnosis of fetal anemia based on the Doppler assessing of peak systolic velocity (PSV) in the fetal middle cerebral artery. The results of Doppler measurements were compared with fetal peripheral blood count estimated after cordocentesis.

Materials And Methods: Doppler measurements of blood flow velocity in the fetal middle cerebral artery were performed in years 2000 and 2001 in 22 pregnancies complicated by maternal blood group alloimmunisation.

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