Dataset of Bessel function maxima and minima to 600 orders and 10000 extrema.

Bessel functions of the first kind are ubiquitous in the sciences and engineering in solutions to cylindrical problems including electrostatics, heat flow, and the Schrödinger equation. The roots of the Bessel functions are often quoted and calculated, but the maxima and minima for each Bessel function, used to match Neumann boundary conditions, have not had the same treatment. Here we compute 10000 extrema for the first 600 orders of the Bessel function .

Exploration of large, rare copy number variants associated with psychiatric and neurodevelopmental disorders in individuals with anorexia nervosa.

Anorexia nervosa (AN) is a serious and heritable psychiatric disorder. To date, studies of copy number variants (CNVs) have been limited and inconclusive because of small sample sizes. We conducted a case-only genome-wide CNV survey in 1983 female AN cases included in the Genetic Consortium for Anorexia Nervosa.

Overview of genetic research in anorexia nervosa: The past, the present and the future.

Background: Even though the evidence supporting the presence of a heritable component in the aetiology of anorexia nervosa (AN) is strong, the underlying genetic mechanisms remain poorly understood. The recent publication of a genome-wide association study (GWAS) of AN (Boraska, Mol Psychiatry, 2014) was an important step in genetic research in AN.

Objective: To briefly sum up strengths and weaknesses of candidate-gene and genome-wide approaches, to discuss the genome-wide association studies of AN and to make predictions about the genetic architecture of AN by comparing it to that of schizophrenia (since the diseases share some similarities and genetic research in schizophrenia is more advanced).

Anorexia nervosa and the Val158Met polymorphism of the COMT gene: meta-analysis and new data.

Objectives: This study aimed to test the association between the Val158Met polymorphism (rs4680) of the catechol-O-methyl transferase gene and anorexia nervosa (AN).

Methods: First, an association study on two cohorts (306 cases and 1009 controls from Utrecht, and 174 cases and 466 controls from Leiden/NTR) was performed. Subsequently, the results were integrated into a meta-analysis, together with all the case-control and family-based studies, which were testing the same hypothesis and were available in the literature.

The Val66Met polymorphism of the BDNF gene in anorexia nervosa: new data and a meta-analysis.

Objectives: The Val66Met polymorphism (rs6265) of the BDNF gene is a non-synonymous polymorphism, previously associated with anorexia nervosa (AN).

Methods: We genotyped rs6265 in 235 patients with AN and 643 controls. Furthermore, we performed a systematic review of all case-control and family-based studies testing this SNP in AN, and combined the results in a meta-analysis.

A meta-analysis of circulating BDNF concentrations in anorexia nervosa.

Objectives: Brain derived neurotrophic factor (BDNF) is involved in neuroplasticity, and in the homeostatic regulation of food intake and energy expenditure. It also has a role in stress responsivity and reward processing. On the basis of its involvement in these various processes, BDNF can be hypothesized to be an important factor in the development and maintenance of anorexia nervosa (AN).

Association study of POMC variants with body composition measures and nutrient choice.

Genome linkage scans and candidate gene studies have implicated the pro-opiomelanocortin (POMC) locus in traits related to food intake, metabolic function, and body mass index. Here we investigate single nucleotide polymorphisms at the POMC locus in order to evaluate the influence of its genetic variance on body fat distribution and diet in a sample of middle-aged men from The Netherlands. 366 Dutch males from the Hamlet cohort were asked detailed questions about food choice, nutrient intake and exercise.

High temperature thermal conductivity of platinum microwire by 3ω method.

The 3ω method for thermal conductivity measurement has emerged as an effective technique applicable to micro/nanowires and thin films. This paper describes the adaptation of the method to temperatures as high as 725 K enabling reliable thermal conductivity measurements on such samples for which previously published methods have been found inadequate. In the technique, a sample wire is heated by applying a sinusoidal current at an angular frequency ω, which causes a temperature and resistance variation at an angular frequency, 2ω, leading to a voltage signal at 3ω.

Are recently identified genetic variants regulating BMI in the general population associated with anorexia nervosa?

The influence of body mass index (BMI) on susceptibility to anorexia nervosa (AN) is not clear. Recently published genome-wide association (GWA) studies of the general population identified several variants influencing BMI. We genotyped these variants in an AN sample to test for association and to investigate a combined effect of BMI-increasing alleles (as determined in the original GWA studies) on the risk of developing the disease.