Background: Lower extremity peripheral artery disease is a problem of contemporary medicine and along with the ischemic heart disease it is considered to be a civilization disease. The risk of the disease increases significantly within a group of people reaching the age of 55 years and is closely related to co-occurring hazardous factors, such as diabetes, hyperlipidemia, hypertension or tobacco smoking. The first symptom reported by patients is intermittent claudication.
View Article and Find Full Text PDFThe male factor is responsible for infertility in about 35-40% of all cases. Idiopathic oligo- and/or astheno- and/or therato-zoospermia is one of the most common male fertility disorders and remains a significant therapeutic challenge. The primary cause of idiopathic male infertility remains unknown but seems to be associated with oxidative stress.
View Article and Find Full Text PDFPurpose: As a rule, wound healing is a natural and spontaneous process. However, in acute or surgical wounds, the wound edges need to be approximated and held together by artificial means. Surgery within the abdominal cavity or elsewhere almost always involves cutting through the skin, after which a medical procedure is conducted, followed by wound closure.
View Article and Find Full Text PDFBackground: The mechanisms of downregulation of protective immunity against Helicobacter pylori (Hp) infection strongly depend on dendritic cell (DC)-induced T-lymphocyte differentiation pattern. Lactic acid bacteria (LAB) strains can modulate Hp-induced immunoresponse by changes in DC activation profiles. Here, we want to find out if the LAB-pulsed DCs will change Hp-induced T-cell responsiveness patterns.
View Article and Find Full Text PDFThe aim of this study was to find out if selected lactic acid bacteria (LAB) strains (antagonistic or nonantagonistic against H. pylori in vitro) would differ in their abilities to modulate the DCs maturation profiles reflected by their phenotype and cytokine expression patterns. Methods.
View Article and Find Full Text PDFIntroduction: In an era of ubiquitous computing, a considerable part of the population, regardless of age group, spend more time in a sitting position. Long-term, static loading of the spine increases muscle tension, leading to the occurrence of pain. Physiotherapy is recommended as primary and secondary prevention of spinal pain symptoms.
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