Cerebrovascular regulation in patients with active tumors and an acute ischemic stroke: a retrospective analysis.

Introduction: Ischemic stroke in patients with a systemic tumor disease or cancer not in remission (active tumors) is less well understood. Some aspects of such paraneoplastic strokes remind on a generalized cerebrovascular disorder. We hypothesized that cerebrovascular regulation in active tumor patients with a stroke is different from other patients with stroke who have no active tumor disease.

Quantification of dynamic cerebral autoregulation and CO dynamic vasomotor reactivity impairment in essential hypertension.

The study of dynamic cerebral autoregulation (DCA) in essential hypertension has received considerable attention because of its clinical importance. Several studies have examined the dynamic relationship between spontaneous beat-to-beat arterial blood pressure data and contemporaneous cerebral blood flow velocity measurements (obtained via transcranial Doppler at the middle cerebral arteries) in the form of a linear input-output model using transfer function analysis. This analysis is more reliable when the contemporaneous effects of changes in blood CO tension are also taken into account, because of the significant effects of CO dynamic vasomotor reactivity (DVR) upon cerebral flow.