Mycophenolatemofetil for immunosuppression after liver transplantation: a follow-up study of 191 patients.

Background: Mycophenolatemofetil (MMF) combined with calcineurin inhibitors (CNIs) as immunosuppression after orthotopic liver transplantation (OLT) is still under discussion. We retrospectively investigated the immunosuppressive potency of MMF for treatment of steroid-resistant acute rejection (AR) or chronic rejection (CR), chronic graft dysfunction, and CNI-induced toxicity in patients after OLT.

Methods: Between 1988 and 2001 we performed 1386 OLTs in 1258 patients.