Publications by authors named "Mardou van Leeuwenstijn-Koopman"
Introduction: We disclosed amyloid positron emission tomography (PET) results in individuals with subjective cognitive decline (SCD) and studied patient experiences and outcomes over a 6-month period.
Methods: Fifty-seven participants from the Subjective Cognitive Impairment Cohort (SCIENCe) (66 ± 8 years, 21 [37%] F, Mini-Mental State Examination 29 ± 1, 15 [26%] amyloid positive [A+]) completed questionnaires 1 week prior (T0), 1 day after (T1), and 6 months after amyloid PET disclosure (T2). Questionnaires addressed patient-reported experiences and outcomes.
Article Synopsis
- The study investigates the sleep issues faced by memory clinic patients with subjective cognitive decline (SCD) and how these problems relate to cognition, mental health, and biomarkers.
- Out of 308 subjects, 64% reported sleep problems, with 35% indicating sleep apnea and 53% suffering from poor sleep quality.
- The findings suggest that enhancing sleep quality could be a potential treatment avenue for alleviating cognitive complaints in SCD patients, as those with sleep problems showed higher levels of depression and anxiety.
As nutrition is one of the modifiable risk factors for cognitive decline, we studied the relationship between dietary quality and clinical characteristics in cognitively normal individuals with subjective cognitive decline (SCD). We included 165 SCD subjects (age: 64 ± 8 years; 45% female) from the SCIENCe project, a prospective memory clinic based cohort study on SCD. The Dutch Healthy Diet Food Frequency Questionnaire (DHD-FFQ) was used to assess adherence to Dutch guidelines on vegetable, fruit, fibers, fish, saturated fat, trans fatty acids, salt and alcohol intake (item score 0-10, higher score indicating better adherence).
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