Publications by authors named "Mardone Cavalcante Franca"
Background: Zinc is an important cause of morbidity, particularly among young children. The dietary, functional, and biochemical indicators should be used to assess zinc status and to indicate the need for zinc interventions.
Objective: The purpose of this study was to determine the zinc status and reference intervals for serum zinc concentration considering dietary, functional, and biochemical indicators in apparently healthy children in the Northeast Region of Brazil.
Background: Zinc is an essential nutrient that is required for numerous metabolic functions, and zinc deficiency results in growth retardation, cell-mediated immune dysfunction, and cognitive impairment.
Objective: This study evaluated nutritional assessment methods for zinc supplementation in prepubertal non-zinc-deficient children.
Design: We performed a randomised, controlled, triple-blind study.
Background: The prevalence of abnormal nutritional status has increased in children and adolescents. Nutritional assessment is important for monitoring the health and nutritional status. Bioelectrical impedance vector analysis (BIVA) combines changes in tissue hydration and structure and body composition that can be assessed.
View Article and Find Full Text PDFArticle Synopsis
- A study was conducted on 30 healthy children aged 8 to 9 years to analyze the effects of 3 months of oral zinc supplementation on their iron status.
- The children were divided into a control group receiving a placebo and an experimental group receiving 10 mg of zinc daily, with blood samples taken at various intervals.
- While zinc supplementation significantly increased serum zinc levels and improved overall nutrient intake, it was found to decrease serum iron levels without leading to anemia.
Zinc is an essential micronutrient for growth and development. Its deficiency causes growth retardation in children and adolescents. The present study analyzes the effect of zinc on growth hormone (GH) secretion, insulin-like growth factor 1 (IGF1), and insulin-like growth factor-binding protein 3 (IGFBP3) in normal children before puberty.
View Article and Find Full Text PDFBerardinelli-Seip syndrome (BSS) is a very rare disorder characterized by near-complete absence of adipose tissue from birth or early infancy, hypoleptinemia, hypertriglyceridemia, insulin resistance, diabetes mellitus, and other clinical signals. It is caused by mutations in AGPAT2 or Gng3lg. We evaluated 10 BSS patients and 10 healthy subjects.
View Article and Find Full Text PDFBackground/aims: Berardinelli-Seip syndrome (BSS), also termed congenital generalized lipodystrophy or congenital generalized lipoatropic diabetes, is a rare autosomal recessive disease characterized by the nearly complete absence of metabolically active adipose tissue from birth, extreme insulin resistance, diabetes mellitus, and hepatomegaly. The aim of this study was to evaluate the effect of diet intervention and oral zinc supplementation on the metabolic control of BSS patients.
Methods: During a 3-month period, 10 BSS patients received individualized diets and oral zinc supplementation.
Objective: The purposes of this study were to investigate the kinetics of zinc in schoolchildren between the ages of 6 and 9 years, of both sexes, and to verify its sensitivity in detecting alterations in body zinc status.
Methods: Nutritional assessment was performed by body mass index. Food intake, venous zinc tolerance test, and zinc kinetics were carried out before and after 3-month oral zinc supplementation.
Purpose: To evaluate the association between the adult mortality, in the age range between 10 and 64 years old in 2000, and socioeconomic indicators for 16 metropolitan regions of Brazil.
Methods: From the datas of the Mortality System from the Ministry of Heath, were calculated the crude mortality rates (CMR) to all the causes of dead and sex, for the 16 metropolitan regions in Brazil. As a form of guarantee the spacial camparability, the CMR were standardized by age and sex, achieving the total mortality-standardized rates and for sex by the direct method of standardization.