Publications by authors named "Marcus K L Lai"

Article Synopsis
  • A clinical trial evaluated the effects of gradual vs. immediate brace weaning protocols on curve stability and health-related quality of life (HRQoL) in patients with adolescent idiopathic scoliosis (AIS).
  • The study involved 369 eligible patients, randomized into two groups: one continued wearing the brace gradually before stopping completely, while the other removed the brace immediately.
  • Results measured changes in spinal curvature and truncal balance at various intervals, with additional assessments of HRQoL over a 24-month period.
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Background: Lumbar disc degeneration (LDD) may be related to aging, biomechanical and genetic factors. Despite the extensive work on understanding its etiology, there is currently no automated tool for accurate prediction of its progression.

Purpose: We aim to establish a novel deep learning-based pipeline to predict the progression of LDD-related findings using lumbar MRIs.

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Aims: The aim of this study was to determine the differences in spinal imaging characteristics between subjects with or without lumbar developmental spinal stenosis (DSS) in a population-based cohort.

Methods: This was a radiological analysis of 2,387 participants who underwent L1-S1 MRI. Means and ranges were calculated for age, sex, BMI, and MRI measurements.

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Aims: To study the associations of lumbar developmental spinal stenosis (DSS) with low back pain (LBP), radicular leg pain, and disability.

Methods: This was a cross-sectional study of 2,206 subjects along with L1-S1 axial and sagittal MRI. Clinical and radiological information regarding their demographics, workload, smoking habits, anteroposterior (AP) vertebral canal diameter, spondylolisthesis, and MRI changes were evaluated.

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Study Design: Cross-sectional study.

Objectives: To define multilevel lumbar developmental spinal stenosis (DSS) using a composite score model and to determine its prevalence.

Methods: This was a cohort study of 2385 openly recruited subjects with lumbosacral (L1-S1) MRIs.

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Lumbar developmental spinal stenosis (DSS) refers to multilevel pre-existing narrowed spinal canals, which predispose to neural compromise. The objective of this study is to identify any inheritance pattern of DSS by utilizing pedigree charts. This was a case series of 13 families with a total of 80 subjects having magnetic resonance imaging (MRI) from L1 to S1.

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Purpose: To systematically evaluate any consensus for the etiology, definition, presentation and outcomes of developmental lumbar spinal stenosis (DLSS).

Methods: A comprehensive literature search was undertaken by 2 independent reviewers with PubMed, Ovid, and Web of Science to identify all published knowledge on DLSS. Search terms included "developmental spinal stenosis" or "congenital spinal stenosis" and "lumbar".

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