Publications by authors named "Marcus D Rushing"
Article Synopsis
- * The study focuses on two versions of the SodC protein produced by Salmonella Typhimurium (SodCI and SodCII), noting that only SodCI effectively functions inside macrophages during infection.
- * Researchers discovered that SodCI binds to peptidoglycan in bacteria, which helps it stay attached and active, and altering SodCII's structure can give it similar binding abilities, enhancing its protective role against the immune response.
Salmonella Typhimurium combats phagocytic superoxide by producing the periplasmic superoxide dismutase, SodCI. The homologous protein, SodCII, is also produced during infection, but does not contribute to virulence. The proteins physically differ in that SodCI is dimeric, protease resistant and non-covalently tethered within the periplasm.
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