Publications by authors named "Marcus Borin"
Background: Gaucher's disease (GD), a lysosomal storage disorder, poses significant treatment challenges. This 23-year study assesses survival rates and treatment efficacy in Brazilian GD patients, integrating data from a 16-year cohort (2000-2015) and the TABNET/DATASUS medicines distribution data (1999-2022).
Objective: To investigate the survival of GD patients in Brazil, identifying key risk factors and evaluating the impact of treatments funded by the Brazilian National Health System (SUS).
Article Synopsis
- - Sewage surveillance is a useful method for detecting viruses in local communities and can help track outbreaks and emerging health threats, as demonstrated in Belo Horizonte, Brazil through the detection of the Mpox virus in wastewater samples over 9 months.
- - The study found varied detection rates of MPXV DNA, with higher rates in hospital wastewater (40%) compared to municipal wastewater (13.3%), likely influenced by the low number of reported MPXV cases and dilution from large populations served by wastewater treatment plants.
- - In addition to MPXV, nine other virus families were identified, including SARS-CoV-2, highlighting the potential of genomic sewage surveillance as a key public health tool for monitoring diverse viral activity in both hospital and community settings
Several countries maintain universal health coverage, which implies responsibility to organize delivery formats of healthcare services and products for citizens. In Brazil, the health system has a principle of universal access for more than 30 years, but many deficiencies remain and the country observes a day practice for those seeking judicial decisions to determine provision of healthcare.
View Article and Find Full Text PDFBackground And Objective: Managed entry agreements (MEAs) consist of a set of instruments to reduce the uncertainty and the budget impact of new high-priced medicines; however, there are concerns. There is a need to critically appraise MEAs with their planned introduction in Brazil. Accordingly, the objective of this article is to identify and appraise key attributes and concerns with MEAs among payers and their advisers, with the findings providing critical considerations for Brazil and other high- and middle-income countries.
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