Publications by authors named "Marcus Blaum"
We report a case of a previously undiagnosed panhypopituitarism initially presenting as a full-blown Addisonian crisis with hypoglycemia, hyponatremia, hypotension and neuropsychological symptoms, more than 30 years after a severe traumatic brain injury (TBI). The patient also displayed clearly visible pathognomonic clinical signs of long-standing pituitary dysfunction. The case highlights the importance of being aware of endocrine sequelae even decades after serious TBI.
View Article and Find Full Text PDFUnlabelled: To date, the use of structural MR imaging (including contrast-enhanced and T2-weighted or fluid-attenuated inversion recovery-weighted images) is the standard method to diagnose tumor progression and to assess antiangiogenic treatment effects. However, several studies have suggested that O-(2-(18)F-fluoroethyl)-L-tyrosine ((18)F-FET) PET adds valuable clinical information to the information derived from structural MR imaging alone. We evaluated the effectiveness and cost-effectiveness of the addition of (18)F-FET PET to structural MR imaging for the management of treatment with bevacizumab and irinotecan (BEV/IR) in patients with recurrent high-grade glioma compared with MR imaging alone from the perspective of the German Statutory Health Insurance.
View Article and Find Full Text PDFUnlike atrophy of the corpus callosum (CC), callosal hypertrophy is a rare neuroimaging finding with only few reported patients. The "megalencephaly, mega CC, and complete lack of motor development" syndrome is morphologically characterized by generalized megalencephaly, a thickened CC, and extensive polymicrogyria causing a pachygyric appearance. We report on the fifth patient showing this rare syndrome, a 3-year-old girl displaying the typical neuroimaging features.
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- The text discusses a rare case of a cellular intraventricular schwannoma located in the fourth ventricle of the brain, which is the first of its kind reported.
- A 71-year-old woman was hospitalized after a CT scan revealed a tumor in the fourth ventricle, which was successfully removed through microsurgery.
- The histopathological analysis confirmed it as a benign schwannoma, highlighting that although rare, such tumors should be considered in the diagnosis of ventricular lesions.
The aim of this study was to compare the diagnostic sensitivity, specificity, and image quality of conventional B-mode US (BM) and phase-inversion tissue harmonic imaging (PTHI) regarding pancreatic pathology. In a prospective study, 107 patients, aged between 28 and 85 years, underwent US examinations of the pancreas with both BM and PTHI in a randomly chosen order. As diagnostic reference, either contrast-enhanced CT or MRI examinations of the upper abdomen were obtained in all patients.
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- The study compared two ultrasound imaging techniques—phase-inversion tissue harmonic imaging and fundamental B-mode sonography—for evaluating kidney focal lesions in 114 patients.
- Results showed that phase-inversion tissue harmonic imaging had significantly higher sensitivity (87.7%) and accuracy (83.1%) compared to fundamental B-mode sonography (65.8% sensitivity and 64.0% accuracy).
- The phase-inversion technique also provided better overall image quality and lesion visibility, resulting in changed patient management in six cases, highlighting its superiority in kidney imaging.