Publications by authors named "Marcos Vinicius Lima de Oliveira Francisco"

: The chikungunya virus (CHIKV), transmitted by infected Aedes mosquitoes, has caused a significant number of infections worldwide. In Brazil, the emergence of the CHIKV-ECSA genotype in 2014 posed a major public health challenge due to its association with more severe symptoms. : This study aimed to shed new light on the host immune response by examining the whole-blood transcriptomic profile of both CHIKV-acute and chronically infected individuals from Feira de Santana, Bahia, Brazil, a region heavily affected by CHIKV, Dengue, and Zika virus epidemics.

View Article and Find Full Text PDF
Article Synopsis
  • Encephalitis, a serious brain condition, is often caused by common viruses like herpes and enteroviruses, but the role of arboviruses in Brazil is less understood.
  • A study from 2020 to 2022 tested samples from patients experiencing encephalitis using advanced molecular and serological techniques.
  • Among 43 evaluated patients, 37.2% showed positive results for various viruses, with chikungunya virus (CHIKV) being the most frequently detected, highlighting its significance in encephalitis cases during outbreaks in Brazil.
View Article and Find Full Text PDF
Article Synopsis
  • * It involved 302 women with a median age of 26, revealing high seroprevalence rates: 57% for Zika, 91.4% for Dengue, and only 7.6% for Chikungunya, despite many participants unaware of any previous infections.
  • * The findings indicate significant past infections of Zika and Dengue, but a majority remain susceptible to Chikungunya, underscoring the need for preventive measures and ongoing epidemiological monitoring in high-risk areas
View Article and Find Full Text PDF

Dengue fever is among the most significant public health concerns in Brazil. To date, the highest number of Dengue notifications in the Americas has been reported in Brazil, with cases accounting for a total number of 3,418,796 reported cases as of mid-December 2022. Furthermore, the northeastern region of Brazil registered the second-highest incidence of Dengue fever in 2022.

View Article and Find Full Text PDF

Zika virus cases in Brazil have diminished since emergence in 2015. We report Guillain Barré Syndrome caused by Zika and possible Chikungunya co-infection during an expected low arboviral season. This case highlights the importance of clinical vigilance for Zika in those with neurological syndromes outside typical arboviral season.

View Article and Find Full Text PDF
Article Synopsis
  • Salvador was significantly impacted during the 2015 Zika virus outbreak, prompting a study involving parturients (pregnant women) and their newborns.
  • The study found that 6.9% of parturients tested positive for Zika virus (ZIKV), with higher rates of exposure to dengue (DENV) and Chikungunya (CHIKV) reflected in antibody tests.
  • The results emphasized the importance of prenatal and neonatal screening for ZIKV and CHIKV due to the occurrence of congenital infections observed in 16.5% of newborns for ZIKV and 13% for CHIKV.
View Article and Find Full Text PDF