A strain-based model for mechanical hemolysis based on a coarse-grained red blood cell model.

Mechanical hemolysis is a major concern in the design of cardiovascular devices, such as prosthetic heart valves and ventricular assist devices. The primary cause of mechanical hemolysis is the impact of the device on the local blood flow, which exposes blood elements to non-physiologic conditions. The majority of existing hemolysis models correlate red blood cell (RBC) damage to the imposed fluid shear stress and exposure time.

Influence of flexibility on the aerodynamic performance of a hovering wing.

In the present study, a computational investigation was carried out to understand the influence of flexibility on the aerodynamic performance of a hovering wing. A flexible, two-dimensional, two-link model moving within a viscous fluid was considered. The Navier-Stokes equations governing the fluid dynamics were solved together with the equations governing the structural dynamics by using a strongly coupled fluid-structure interaction scheme.