Publications by authors named "Marcos Torres-Roca"
Article Synopsis
- - The study aimed to explore how TFE3 rearrangement affects recurrence in renal cell carcinoma (RCC) and emphasized the importance of immunohistochemistry (IHC) in the diagnostic process.
- - Among 695 RCC patients, 22 showed signs of TFE3 rearrangement, with FISH testing confirming 8 had TFE3-rearranged-RCC, which was associated with a significantly higher recurrence rate compared to clear cell RCC (50% vs 18.8%).
- - The findings indicate that TFE3 rearrangement is a key independent prognostic factor for recurrence and shorter progression-free survival, highlighting the need for further studies and careful patient follow-up.
A 76-year-old man undergoing hormone therapy for prostate cancer was referred for 68 Ga-PSMA-11-PET (PSMA PET) due to persistently detectable PSA level. No PSMA-positive tumor lesions were detected, so a delayed phase imaging was performed, which revealed focal PSMA uptake in the right seminal vesicle together with contrast accumulation on excretory phase contrast-enhanced CT. These findings were finally determined to be secondary to urinary reflux as a consequence of a prostatic enucleation he had undergone 5 months earlier following an episode of acute urinary retention.
View Article and Find Full Text PDFPurpose: Our aim was to assess oncologic, safety, and quality of life-related outcomes of focal therapy with irreversible electroporation in men with localized prostate cancer.
Materials And Methods: This was a single-center, phase II study.
Inclusion Criteria: prostate cancer International Society of Urological Pathology grade 1-2, prostate specific antigen ≤15 ng/ml, ≤cT2b.
What is the impact of post-radical prostatectomy urinary incontinence on everyday quality of life? Linking Pad usage and International Consultation on Incontinence Questionnaire Short-Form (ICIQ-SF) for a COMBined definition (PICOMB definition).
Neurourol Urodyn
March 2021
Article Synopsis
- The study looked at how to define urinary continence (UC) for patients after prostate surgery, focusing on their quality of life (QoL).
- Researchers checked 634 patients' urinary issues one year post-surgery, using questionnaires and counting how many pads they used in a day.
- The results suggested using a combined definition of "0 pads" and an ICIQ score of 2 or less to show the best quality of life for patients dealing with urine leakage.
Article Synopsis
- The study investigates the link between anogenital distance (AGD) and the risk of prostate cancer (CaP), aiming to expand on previous research about AGD as an indicator of prenatal androgen levels.
- A case-control study involved 260 men, where AGD measurements were taken, and the relationship between AGD and CaP was analyzed using various statistical methods.
- Results indicated that AGD could be a helpful clinical marker for diagnosing CaP, particularly in certain patient subgroups, despite its moderate sensitivity and specificity.
Article Synopsis
- The study looked at the connection between how far certain body parts are from each other (anogenital distance) and the risk of prostate cancer in men.
- Researchers measured this distance in 260 men, some with prostate cancer and some without, to see if it made a difference.
- They found that men with shorter anogenital distances were more likely to have prostate cancer compared to those with longer distances.
Article Synopsis
- - The study evaluated the connection between anogenital distance (AGD), a marker of prenatal androgen exposure, and the severity and prognosis of prostate cancer in 119 patients.
- - Researchers measured two types of AGD and conducted logistic regression analysis to determine their association with prostate cancer outcomes, focusing on biochemical recurrence and surgical specimen margins.
- - Results indicate that longer AGD, linked to higher prenatal androgen exposure, correlates with worse prognosis in prostate cancer cases.
Background: Anogenital distance (AGD), the distance from the centre of the anus to the genitals, is a sexually dimorphic phenotype in mammals. Experimental studies have shown that AGD is a biomarker of prenatal androgen exposure during the masculinisation period of development. The aim of this study is to assess the relationship between anogenital distance (AGD), as an indirect marker of prenatal hormonal environment, and prostate cancer (PCa) severity.
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