Publications by authors named "Marcos T Augusto"

Article Synopsis
  • Chikungunya virus (CHIKV) has been spreading variably across Brazil, and its impact in São José do Rio Preto (SJdRP) is studied to understand the low incidence of reported cases, despite the potential for underdiagnosis due to overlapping symptoms with other viruses like dengue.
  • A study involving 341 asymptomatic individuals over four years showed an increase in anti-CHIKV IgG seroconversion from 0.35% to 2.3%, and 4.4% of dengue-suspected individuals tested positive for anti-CHIKV IgM during a 2019 outbreak.
  • Genomic analysis confirmed the presence of the ECSA genotype of CHIKV in SJd
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Arbovirus infections are increasingly important causes of disease, whose spectrum of neurological manifestations are not fully known. This study sought to retrospectively assess the incidence of arboviruses in cerebrospinal fluid samples of patients with neurological symptoms to inform diagnosis of central and peripheral nervous system disorders. A total of 255 cerebrospinal fluid (CSF) samples collected from January 2016 to December 2017 were tested for dengue virus (DENV 1-4), Zika virus (ZIKV), and Chikungunya virus (CHIKV) in addition to other neurotropic arboviruses of interest, using genetic and serologic assays.

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Enterovirus (EV) is commonly associated with central nervous system (CNS) syndromes. Recently, gastroenteric viruses, including rotavirus (RVA), human astrovirus (HAstV), and norovirus (NoV), have also been associated with CNS neurological disorders. The aim of the present study was to investigate the presence of EV, RVA, HAst, and NoV associated to CNS infections with undiagnosed etiology in Northwest region of São Paulo State, Brazil, and to conduct the molecular characterization of the positive samples detected.

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Measles is an acute and highly contagious but vaccine-preventable infectious disease. Despite years of being considered eliminated, decreased vaccination rates have produced virus reemergence in several countries, including Brazil. Measles can be controlled through immunization programs, through which aim to achieve 95% coverage with two doses of the vaccine.

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