Impact of light spectrum electromagnetic radiation variations on performance and hormonal profiles in laying hens.

Avian photopic curves show energy peaks at different wavelengths than humans, particularly in the ultraviolet, yellow, and red range. Therefore, an illumination system with a spectrum tailored for laying hens, encompassing the entire visible spectrum, can enhance performance and welfare. The primary contribution of this study was the development of two Spectral Power Distributions (SPDs) specifically designed for laying hens, with different spectral proportions (S1 and S2), and the evaluation of their effects on productive performance, egg quality, and hormonal levels, compared to conventional white lighting at 3000 K (C).

Analgesic and Anti-Arthritic Potential of Methanolic Extract and Palmatine Obtained from Leaves.

: is used in folk medicine to treat pain and arthritis. Palmatine is an alkaloid isolated from several plants, including leaves. The aim of the present study was to investigate the analgesic, anti-arthritic, and anti-inflammatory potential of the methanolic extract of (EMAS) and palmatine.

Honey and Aloe vera Solution Increases Survival and Modulates the Tumor Size In Vivo.

Scope: The combination of honey and Aloe vera is used as a popular complementary treatment for cancer due to their nutraceutical properties. This study aims to investigate the anticancer activity of honey and A. vera solution and its ethanolic extraction through in vitro and in vivo approaches.

Tempol effect on oxidative and mitochondrial markers in preclinical models for prostate cancer.

Background: Tempol is a redox-cycling nitroxide considered a potent antioxidant. The present study investigated the tempol effects on oxidative stress and mitochondrial markers on prostate cancer (PCa).

Methods: PC-3 and LnCaP cells were exposed to tempol.

Two new naphthoquinone derivatives from (Gesneriaceae).

Two new naphthoquinones, 7-hydroxy-2--methyldunniol () and 7-methoxy-2--methyldunniol () were isolated from the tubers of (Seem.) G. Nicholson (Gesneriaceae).

Absence of maternal-fetal adverse effects of . Beauv. following treatment during pregnancy in mice.

P. Beauv is a plant native to Brazil that exhibits various beneficial activities including antioxidant, antibacterial, antifungal, antiprotozoal, anti-hyperalgesic, and anti-inflammatory properties. The aim of this study was to assess the impact of the ethanol extract of (EEAl) on reproductive outcomes, embryofetal development, and DNA integrity of pregnant female mice.

Diversity of bacterial and fungal endophytic communities presents in the leaf blades of Sinningia magnifica, Sinningia schiffneri and Sinningia speciosa from different cladus of Gesneriaceae family: A comparative analysis in three consecutive years.

Sinningia is a genus of plants of Gesneriaceae family with species native to Brazil and is a source of several classes of bioactive secondary metabolites, such as quinones, terpenoids, flavonoids, and phenylethanoid glycosides. However, the diversity of endophytic microorganisms associated with them and the impact of endophytes on the biosynthesis of bioactive substances is unknown. Therefore, we sought to evaluate the microbial diversity, behavior, and frequency of endophytes in leaves blades of S.

The Ethanolic Extract of Mart. Does Not Alter Reproductive Performance or Embryo-Fetal Development, nor Does It Cause Chromosomal Damage.

is a native Brazilian plant found in the State of Mato Grosso do Sul. It is used in folk medicine to treat kidney diseases, skin diseases, infections, rheumatism, gastrointestinal diseases, and respiratory diseases. It is also used as an abortifacient.

Three new diterpenoids from the leaves of .

Three new diterpenoids, demethylfruticuline B (), 20-hydroxyfruticuline B (), and 6-hydroxyisofruticuline A () were isolated from the leaves of Benth, together with five known compounds: fruticuline B (), fruticuline A (), demethylfruticuline A (), heterobetulinic acid (), and maslinic acid (). The known compounds - are being reported for the first time in this species. Compounds and - were tested for antioxidant activity using the ORAC-FL method, and the antioxidant capacity was measured as relative trolox equivalent.

Essential Oil Increases the Effect of Digluconate Chlorhexidine on Microcosm Biofilms.

The aim of this study was to evaluate the effect of the essential oil and its association with chlorhexidine on cariogenic microcosm biofilm composition and acidogenicity. Minimum inhibitory and bactericide concentrations from the essential oil and chlorhexidine were determined by broth microdilution assay. Microcosms (polymicrobial) biofilms were produced on glass coverslips, using inoculum from human saliva in McBain culture medium (0.

Preclinical safety evaluation of the ethanolic extract from the aerial parts of Gomphrena celosioides Mart. in rodents.

The toxicological potential of the ethanolic extract from Gomphrena celosioides (EEGC), a medicinal plant used as a natural analgesic, was investigated in acute and subacute toxicity models in rodents. For the acute toxicity test, 2000 mg/kg of EEGC was administered orally to male and female Wistar rats, while Swiss mice received 75, 150 or 300 mg/kg of EEGC for the subacute toxicity test. Animals treated with an only dose of 2000 mg/kg EEGC showed no clinical signs of toxicity, indicating that the LD is higher than this dose.

Antioxidant effects of bis-indole alkaloid indigo and related signaling pathways in the experimental model of Duchenne muscular dystrophy.

Indigo is a bis-indolic alkaloid that has antioxidant and anti-inflammatory effects reported in literature and is a promissory compound for treating chronic inflammatory diseases. This fact prompted to investigate the effects of this alkaloid in the experimental model of Duchenne muscular dystrophy. The main aim of this study was to evaluate the potential role of the indigo on oxidative stress and related signaling pathways in primary skeletal muscle cell cultures and in the diaphragm muscle from mdx mice.

The NO-cGMP-K+ Channel Pathway Participates in Diuretic and Cardioprotective Effects of Blutaparon portulacoides in Spontaneously Hypertensive Rats.

is a Brazilian plant species that is widely used in folk medicine. The present study investigated the role of an aqueous extract of against hypertension in spontaneously hypertensive rats. The aqueous extract of was obtained from the whole plant.

Three new naphthoquinones from the tubers of .

Three new naphthoquinones, 5,6,7-trimethoxydunnione (), 6,7-dimethoxy-α-dunnione (), and 5,6,7-trimethoxydunniol () were isolated from the tubers of Chautems, together with eleven known compounds: 5-hydroxy-6,7-dimethoxy-α-dunnione (), 6-hydroxy-7-methoxy-α-dunnione (), 7-hydroxy-6-methoxy-α-dunnione (), cedrol (), tectoquinone (), plantainoside A (), calceolarioside A (), calceolarioside B (), sanangoside (), -calceolarioside A (), and conandroside (). The known compounds , - and - are being reported for the first time in this species. Hexane, ethyl acetate and ethanol extracts were tested for antioxidant activity by the ORAC-FL method, and the antioxidant capacity was measured as trolox equivalent (TE).

Evaluation of antimicrobial and antiproliferative activities of Actinobacteria isolated from the saline lagoons of northwestern Peru.

Extreme environments Morrope and Bayovar Salt lagoons, several ecosystems and microhabitats remain unexplored, and little is known about the diversity of Actinobacteria. We suggest that the endemic bacteria present in this extreme environment is a source of active molecules with anticancer, antimicrobial, and antiparasitic properties. Using phenotypic and genotypic characterization techniques, including 16S rRNA sequencing, we identified these bacteria as members of the genera Streptomyces, Pseudonocardia, Staphylococcus, Bacillus, and Pseudomonas.

Anti-inflammatory Properties of Ethanolic Extract and 2″-O-β-D-Glucopyranosyl-vitexin Obtained from Alternanthera tenella Colla Whole Plant.

Six flavonoids were identified and isolated from the ethanolic extract of Alternanthera tenella Colla (Amaranthaceae) whole plant (EEAT) including 2″-O-β-D-glucopyranosyl-vitexin (A19). Flavonoids have anti-inflammatory activity; however, the 2″-O-β-D-glucopyranosyl-vitexin anti-inflammatory property was not totally explored. The aim of the present study was to investigate the anti-inflammatory effects of ethanolic extract from A.

Antiarthritic and Antihyperalgesic Properties of Ethanolic Extract from Mart. (Amaranthaceae) Aerial Parts.

Mart. (Amaranthaceae) is used in folk medicine as a natural analgesic, and in Brazil, the species of genus is used for rheumatism. However, scientific evidence which supports its popular use as an analgesic is scarce.

Blutaparon portulacoides ethanolic extract reduced IL-1β and inflammatory parameters induced by the Mycobacterium complex and carrageenan in mice.

Information on the health benefits of ethanolic extracts obtained from Blutaparon portulacoides stem (EEBP) hasn´t been consistently described in the literature until the present moment. This study investigated the antimycobacterial, anti-inflammatory and toxicological effects of EEBP in models of inflammation/infection, as well as its chemical composition. Chemical analysis of EEBP by electrospray ionization-mass spectrometry/HPLC-MS/MS identified 3,5,3'-Trihydroxy-4'-methoxy-6,7-methylenedioxy-flavone, gomphrenol, ferulic, vanillic, and caffeic acids.

and Honey Solution and Their Ethanolic Extraction Solution Could Act on Metastasis-Regulating Processes in Walker 256 Tumor Tissues In Vivo?

Research has shown that both and honey have anticancer and nutrition properties, including the inhibition of metastasis. In order to evaluate the effect of a solution of and honey (A) and their ethanolic fraction (F) on metastasis-regulating processes in primary tumors, Wistar rats were subcutaneously implanted with Walker 256 tumors and treated with A and F (670 µl/kg by gavage, daily for 21 days). An analysis of the primary tumor tissues of these animals showed a decrease in N-cadherin expression in groups WA and WF, with a concomitant increase in E-cadherin expression in group WA compared to the control group.

Bioguided identification of antimicrobial compounds from (L.) Roberty root essential oil.

To determine the group of compounds from root essential oil that have antimicrobial activity. Thin-layer chromatography coupled to direct bioautography was used to determinate the fraction(s) having antimicrobial activity against methicillin-resistant  (MRSA) and vancomycin-resistant (VREF). Through GC-MS identification, the fractions with the greatest similarity to the active thin-layer chromatography fraction were used to determinate the MIC.

Chemical composition and antiproliferative, antioxidant and trypanocidal activities of the fruits from (Mart.) O. Berg (Myrtaceae).

Chemical investigation of the extracts of the fruits from resulted in the isolation of six known compounds identified by NMR and comparison with literature data (2',4'-dihydroxy-5'-methyl-6'-methoxychalcone (), 2',4'-dihydroxy-3',5'-dimethyl-6'-methoxychalcone (), 2'-hydroxy-3'-methyl-4',6'-dimethoxychalcone (), 2',6'-dihydroxy-3'-methyl-4'-methoxychalcone (), 5-hydroxy-7-methoxy-8-methylflavanone () and 7-hydroxy-5-methoxy-6-methylflavanone ()). The considerable antioxidant capacity of the extracts was demonstrated by ORAC-FL and DPPH tests. The antiproliferative assay of the extracts and was done , against many different cancer cell lines besides a healthy one.

Anticonvulsant, sedative, anxiolytic and antidepressant activities of the essential oil of Annona vepretorum in mice: Involvement of GABAergic and serotonergic systems.

Annona vepretorum is an endemic species of the Caatinga biome, known in Northeastern Brazil as "araticum" and/or "pinha da Caatinga". In the present study it was evaluated the neuropharmacological potential of the essential oil obtained from the leaves of Annona vepretorum, as well as of the inclusion complexes of oil obtained with cyclodextrin. Thus, were used neuropharmacological tests already consolidated in the literature like open-field, elevated plus maze, rota-rod, tail suspension test, thiopental-induced sleep test, among others.

Antibacterial and antifungal properties of crude extracts and isolated compounds from .

Antimicrobial activity of dichloromethane and ethanol extracts and five compounds: pinostrobin (I), pinocembrin (II), tectochrysin (III), galangin 3-methyl ether (IV) and tiliroside (V) isolated from aerial parts against fifteen microorganisms was determined. The structures of these compounds were elucidated based on ESI-MS and NMR spectroscopic data. Both extracts showed antimicrobial activity against several tested microorganisms.

Anti-Inflammatory and Antioxidant Properties of the Extract, Tiliroside, and Patuletin 3-O--D-Glucopyranoside from (Amaranthaceae).

Brazilian ginseng, including , is used in popular medicine as a natural anti-inflammatory, tonic, analgesic, and antidiabetic agent. In this study, we investigated the chemical composition and evaluated the antioxidant and anti-inflammatory activities of the ethanolic extract as well as the major isolated glycoside flavonoids tiliroside and patuletin 3-O--D-glucopyranoside. Chromatographic techniques and spectroscopic analysis were used for the isolation and identification of the major compounds.