Impact of light spectrum electromagnetic radiation variations on performance and hormonal profiles in laying hens.

Avian photopic curves show energy peaks at different wavelengths than humans, particularly in the ultraviolet, yellow, and red range. Therefore, an illumination system with a spectrum tailored for laying hens, encompassing the entire visible spectrum, can enhance performance and welfare. The primary contribution of this study was the development of two Spectral Power Distributions (SPDs) specifically designed for laying hens, with different spectral proportions (S1 and S2), and the evaluation of their effects on productive performance, egg quality, and hormonal levels, compared to conventional white lighting at 3000 K (C).

Hydroxycinnamic Acid Extraction from Multiple Lignocellulosic Sources: Correlations with Substrate Composition and Taxonomy for Flavoring and Antioxidant Applications.

The extraction of hydroxycinnamic acids (HCADs) is a strategy for lignocellulosic biomass valorization due to their high value-added nature and the possibility of application as flavoring and antioxidants. This study proposes correlations between the composition and taxonomy of 28 globally available agro-industrial feedstocks with the production of HCADs using chemometric tools. Principal component analysis indicated strong correlations between ferulic acid release and hemicellulose type and content, especially in grass biomasses.

Analgesic and Anti-Arthritic Potential of Methanolic Extract and Palmatine Obtained from Leaves.

: is used in folk medicine to treat pain and arthritis. Palmatine is an alkaloid isolated from several plants, including leaves. The aim of the present study was to investigate the analgesic, anti-arthritic, and anti-inflammatory potential of the methanolic extract of (EMAS) and palmatine.

Honey and Aloe vera Solution Increases Survival and Modulates the Tumor Size In Vivo.

Scope: The combination of honey and Aloe vera is used as a popular complementary treatment for cancer due to their nutraceutical properties. This study aims to investigate the anticancer activity of honey and A. vera solution and its ethanolic extraction through in vitro and in vivo approaches.

Tempol effect on oxidative and mitochondrial markers in preclinical models for prostate cancer.

Background: Tempol is a redox-cycling nitroxide considered a potent antioxidant. The present study investigated the tempol effects on oxidative stress and mitochondrial markers on prostate cancer (PCa).

Methods: PC-3 and LnCaP cells were exposed to tempol.

Two new naphthoquinone derivatives from (Gesneriaceae).

Two new naphthoquinones, 7-hydroxy-2--methyldunniol () and 7-methoxy-2--methyldunniol () were isolated from the tubers of (Seem.) G. Nicholson (Gesneriaceae).

Absence of maternal-fetal adverse effects of . Beauv. following treatment during pregnancy in mice.

P. Beauv is a plant native to Brazil that exhibits various beneficial activities including antioxidant, antibacterial, antifungal, antiprotozoal, anti-hyperalgesic, and anti-inflammatory properties. The aim of this study was to assess the impact of the ethanol extract of (EEAl) on reproductive outcomes, embryofetal development, and DNA integrity of pregnant female mice.

Diversity of bacterial and fungal endophytic communities presents in the leaf blades of Sinningia magnifica, Sinningia schiffneri and Sinningia speciosa from different cladus of Gesneriaceae family: A comparative analysis in three consecutive years.

Sinningia is a genus of plants of Gesneriaceae family with species native to Brazil and is a source of several classes of bioactive secondary metabolites, such as quinones, terpenoids, flavonoids, and phenylethanoid glycosides. However, the diversity of endophytic microorganisms associated with them and the impact of endophytes on the biosynthesis of bioactive substances is unknown. Therefore, we sought to evaluate the microbial diversity, behavior, and frequency of endophytes in leaves blades of S.

The Ethanolic Extract of Mart. Does Not Alter Reproductive Performance or Embryo-Fetal Development, nor Does It Cause Chromosomal Damage.

is a native Brazilian plant found in the State of Mato Grosso do Sul. It is used in folk medicine to treat kidney diseases, skin diseases, infections, rheumatism, gastrointestinal diseases, and respiratory diseases. It is also used as an abortifacient.

Three new diterpenoids from the leaves of .

Three new diterpenoids, demethylfruticuline B (), 20-hydroxyfruticuline B (), and 6-hydroxyisofruticuline A () were isolated from the leaves of Benth, together with five known compounds: fruticuline B (), fruticuline A (), demethylfruticuline A (), heterobetulinic acid (), and maslinic acid (). The known compounds - are being reported for the first time in this species. Compounds and - were tested for antioxidant activity using the ORAC-FL method, and the antioxidant capacity was measured as relative trolox equivalent.

Essential Oil Increases the Effect of Digluconate Chlorhexidine on Microcosm Biofilms.

The aim of this study was to evaluate the effect of the essential oil and its association with chlorhexidine on cariogenic microcosm biofilm composition and acidogenicity. Minimum inhibitory and bactericide concentrations from the essential oil and chlorhexidine were determined by broth microdilution assay. Microcosms (polymicrobial) biofilms were produced on glass coverslips, using inoculum from human saliva in McBain culture medium (0.

Preclinical safety evaluation of the ethanolic extract from the aerial parts of Gomphrena celosioides Mart. in rodents.

The toxicological potential of the ethanolic extract from Gomphrena celosioides (EEGC), a medicinal plant used as a natural analgesic, was investigated in acute and subacute toxicity models in rodents. For the acute toxicity test, 2000 mg/kg of EEGC was administered orally to male and female Wistar rats, while Swiss mice received 75, 150 or 300 mg/kg of EEGC for the subacute toxicity test. Animals treated with an only dose of 2000 mg/kg EEGC showed no clinical signs of toxicity, indicating that the LD is higher than this dose.

Antioxidant effects of bis-indole alkaloid indigo and related signaling pathways in the experimental model of Duchenne muscular dystrophy.

Indigo is a bis-indolic alkaloid that has antioxidant and anti-inflammatory effects reported in literature and is a promissory compound for treating chronic inflammatory diseases. This fact prompted to investigate the effects of this alkaloid in the experimental model of Duchenne muscular dystrophy. The main aim of this study was to evaluate the potential role of the indigo on oxidative stress and related signaling pathways in primary skeletal muscle cell cultures and in the diaphragm muscle from mdx mice.

The NO-cGMP-K+ Channel Pathway Participates in Diuretic and Cardioprotective Effects of Blutaparon portulacoides in Spontaneously Hypertensive Rats.

is a Brazilian plant species that is widely used in folk medicine. The present study investigated the role of an aqueous extract of against hypertension in spontaneously hypertensive rats. The aqueous extract of was obtained from the whole plant.

Betulinic acid and its spray dried microparticle formulation: In vitro PDT effect against ovarian carcinoma cell line and in vivo plasma and tumor disposition.

The race against ovarian cancer continue to motivate the research worldwide. It is known that many antitumor drugs have limited penetration into solid tumor tissues due to its microenvironment, thus contributing to their low efficacy. Therapeutic modalities have been exploited to elicit antitumor effects based on microenvironment of tumor, including Photodynamic therapy (PDT).

Three new naphthoquinones from the tubers of .

Three new naphthoquinones, 5,6,7-trimethoxydunnione (), 6,7-dimethoxy-α-dunnione (), and 5,6,7-trimethoxydunniol () were isolated from the tubers of Chautems, together with eleven known compounds: 5-hydroxy-6,7-dimethoxy-α-dunnione (), 6-hydroxy-7-methoxy-α-dunnione (), 7-hydroxy-6-methoxy-α-dunnione (), cedrol (), tectoquinone (), plantainoside A (), calceolarioside A (), calceolarioside B (), sanangoside (), -calceolarioside A (), and conandroside (). The known compounds , - and - are being reported for the first time in this species. Hexane, ethyl acetate and ethanol extracts were tested for antioxidant activity by the ORAC-FL method, and the antioxidant capacity was measured as trolox equivalent (TE).

Anti-inflammatory Properties of Ethanolic Extract and 2″-O-β-D-Glucopyranosyl-vitexin Obtained from Alternanthera tenella Colla Whole Plant.

Six flavonoids were identified and isolated from the ethanolic extract of Alternanthera tenella Colla (Amaranthaceae) whole plant (EEAT) including 2″-O-β-D-glucopyranosyl-vitexin (A19). Flavonoids have anti-inflammatory activity; however, the 2″-O-β-D-glucopyranosyl-vitexin anti-inflammatory property was not totally explored. The aim of the present study was to investigate the anti-inflammatory effects of ethanolic extract from A.

Antibiofilm effects of and essential oils on cariogenic bacteria.

The inhibitory and antibiofilm effects of (EOTv) and essential oils (EOHs) on cariogenic microorganisms were evaluated. The chemical characterization of EOTv was performed by gas chromatography/mass spectrometry. , , , , , and were used for agar diffusion assays and determination of minimal inhibitory and minimal bactericide concentrations.

Comparative evaluation of chemical composition and biological activities of tropical fruits consumed in Manaus, central Amazonia, Brazil.

Fruits are widely recognized as sources of biologically active metabolites, such as antioxidant compounds. In this context, fruits commonly consumed in the central Amazonia, especially in its biggest metropolis (Manaus - AM/Brazil), are attractive as potential sources of antioxidant compounds related to biological activities. Most of such fruits are still poorly studied and/or remain unknown outside the Amazon region.

Antiarthritic and Antihyperalgesic Properties of Ethanolic Extract from Mart. (Amaranthaceae) Aerial Parts.

Mart. (Amaranthaceae) is used in folk medicine as a natural analgesic, and in Brazil, the species of genus is used for rheumatism. However, scientific evidence which supports its popular use as an analgesic is scarce.

Phenotypic detection of quorum sensing inhibition in pyoverdine and swarming by volatile organic products.

To determine phenotypically the anti quorum-sensing (QS) activity of 30 volatile organic products (VOPs) through the inhibition of swarming motility and pyoverdine production in . Twenty-four essential oils and six small volatile organic compounds randomly selected were screened for their anti-QS activity by violacein inhibition on . The VOPs with positive results were subsequently evaluated for swarming motility and pyoverdine production on determining the colony diameter and fluorescence under UV light, respectively.

Blutaparon portulacoides ethanolic extract reduced IL-1β and inflammatory parameters induced by the Mycobacterium complex and carrageenan in mice.

Information on the health benefits of ethanolic extracts obtained from Blutaparon portulacoides stem (EEBP) hasn´t been consistently described in the literature until the present moment. This study investigated the antimycobacterial, anti-inflammatory and toxicological effects of EEBP in models of inflammation/infection, as well as its chemical composition. Chemical analysis of EEBP by electrospray ionization-mass spectrometry/HPLC-MS/MS identified 3,5,3'-Trihydroxy-4'-methoxy-6,7-methylenedioxy-flavone, gomphrenol, ferulic, vanillic, and caffeic acids.

and Honey Solution and Their Ethanolic Extraction Solution Could Act on Metastasis-Regulating Processes in Walker 256 Tumor Tissues In Vivo?

Research has shown that both and honey have anticancer and nutrition properties, including the inhibition of metastasis. In order to evaluate the effect of a solution of and honey (A) and their ethanolic fraction (F) on metastasis-regulating processes in primary tumors, Wistar rats were subcutaneously implanted with Walker 256 tumors and treated with A and F (670 µl/kg by gavage, daily for 21 days). An analysis of the primary tumor tissues of these animals showed a decrease in N-cadherin expression in groups WA and WF, with a concomitant increase in E-cadherin expression in group WA compared to the control group.

Bioguided identification of antimicrobial compounds from (L.) Roberty root essential oil.

To determine the group of compounds from root essential oil that have antimicrobial activity. Thin-layer chromatography coupled to direct bioautography was used to determinate the fraction(s) having antimicrobial activity against methicillin-resistant  (MRSA) and vancomycin-resistant (VREF). Through GC-MS identification, the fractions with the greatest similarity to the active thin-layer chromatography fraction were used to determinate the MIC.