Transplant management in Brazil: a temporal analysis of financial investments and procedures.

Objective: To analyze public management actions regarding organ, cell, and tissue transplant procedures and their financial investments in Brazil.

Method: Mixed (time and place) ecological study, carried out based on data from the Hospital Information System of the Brazilian Public Health System (SUS) Information Technology Department and the National Transplant System, from 2001 to 2023. Temporal trend analyses, descriptive and inferential statistics were performed.

Factors associated with the quality of corneas retrieved for transplantation by Eye Banks: a scoping review protocol.

Introduction: The cornea is an avascular and transparent layer of connective tissue crucial to retinal image quality. Diseases can impair its quality, affecting vision. Keratoplasty is the only therapy capable of restoring vision quality in severe corneal involvement.

A Descriptive Study of Corneal Graft Failure in Retransplant Patients.

Objective: To identify the main predictors for corneal graft failure in patients who underwent retransplantation.

Method: This is a cross-sectional research with a quantitative and analytical approach, conducted based on data from secondary sources of a Human Eye Tissue Bank (HETB) in Northeast Brazil. Data were collected from the medical charts of all patients transplanted between January 2010 and December 2014.

Non-Donors of Organs and Tissues Due to Medical Refusal in a Transplant Referral Service.

Background: Obtaining organs for transplants through a deceased donor occurs exclusively through donation. However, some open protocols with potential donors do not become effective donors due to medical refusal. Our aim was to identify the profile of non-donors of organs and tissues due to medical refusal in a state reference service for transplants.

Global legislation regulating the donation, procurement and distribution processes of organs and tissues from deceased donors for transplants: A scoping review.

Introduction: Organ transplantation is one of the most successful advances in modern medicine. However, a legal system is necessary for its practice to be free from ethical flaws and to respect donors, recipients, and family members.

Objective: To map the global legislation regulating the donation, capture and distribution processes of organs and tissues from deceased donors for transplants.

Interventions for Strengthening General Self-Efficacy Beliefs in College Students: An Integrative Review.

Objective: To assess the evidence regarding the effectiveness of interventions aimed at strengthening self-efficacy beliefs in college students.

Methods: Integrative Review conducted on the Lilacs, PubMed, CinahL, Cochrane Collaboration Databases, Scopus, and PsycInfo databases. The methodological quality of the studies was assessed using tools proposed by the Joanna Briggs Institute, and the results were analyzed descriptively.

Ocular dryness in intensive care: proposal for a new nursing diagnosis.

Objective: to analyze the concept associated with diagnostic proposition Ocular dryness in adult patients hospitalized in an Intensive Care Unit, identifying its attributes, antecedents and consequences.

Methods: a methodological study carried out through concept analysis, operationalized by scoping review.

Results: the analysis of 180 studies allowed the identification of two attributes, 32 antecedents and 12 consequences.

Safety and efficacy of silicone tape for indwelling urinary catheter fixation in intensive care patients-A randomized clinical trial.

Background: Critically ill patients are more vulnerable to medical adhesive-related skin injuries (MARSI), whose prevention is a constant challenge and one of the main quality indicators of nursing care. MARSI associated with indwelling urinary catheter (IUC) fixation is a relevant adverse event, mainly because of the constant involuntary traction and high skin vulnerability of the fixation site. Silicone adhesive tape has appreciable qualities for fragile skin among the range of adhesives, leading to the inference that it reduces the risk of MARSI.

Penitentiary health team: the reality of the work process.

This article aims to characterize the work process of the prison health team in the state of Paraíba. This is an exploratory research, with a qualitative approach, carried out with two Prison Primary Care Teams in the state of Paraíba. Individual interviews were carried out with health professionals in order to elucidate the work process developed.

Technologies used in ruminant grazing management: an integrative review.

The objective of this study was to identify the main technologies used in the management of ruminant grazing. We developed a review protocol in which the search terms were previously tested and based on the PVO strategy to determine the guiding question (population [P]: domestic ruminants; variables [V] of interest: grazing management technologies; and outcomes [O]: intake, performance, and productivity of animals raised exclusively on pasture). The guiding question was the following: What technologies are used in the grazing management of domestic ruminants on pasture? The databases used were SCOPUS (Elsevier), SciELO Citation Index, Science Direct, and Wiley Online Library, and the search was carried out until October 15, 2021.

Costs related to obtaining organs for transplantation: A systematic review.

Introduction: The number of transplants in the world is growing, although there is a demand that exceeds supply. It is worth mentioning that the costs for obtaining organs are considered high. However, few studies have been developed on analyzing the costs of obtaining organs and tissues for transplants in order to support the decision-making of managers and health professionals.

Donation Process and Evaluation of Corneal Tissue in a Slit Lamp.

Background: The process of capturing and classifying the viability of corneal tissue for corneal transplantation is complex. The biomicroscopic examination is one of the techniques used to evaluate the quality of corneal tissues. The aim of this study was to analyze the relationship between the evaluation criteria used in biomicroscopic examination using a slit lamp and the classification of the quality of corneal tissue.

Analysis of factors associated with hematopoietic stem-cell retransplantation: a case-control study.

Objective: to analyze the factors associated with the failure of Hematopoietic Stem Cell Transplantation (HSCT) in patients undergoing Hematopoietic Stem Cell Retransplantation (HSCR).

Method: this study implemented a quantitative approach and was a case-control type which addressed patients undergoing HSCR. To do so, a paired sample of two controls was used for each case (2:1).

Analysis of the temporal trend of mortality from sickle cell anemia in Brazil.

Objectives: To analyze the temporal trend of mortality from sickle cell anemia in Brazil, by region, in the period 1997-2017.

Methods: epidemiological study, with an ecological design, with a temporal trend, carried out with data from the Mortality Information System. For descriptive analysis, absolute and relative frequencies were used.

HIV/AIDS and the social determinants of health: a time series study.

Objective: To analyze the time trend, spatial distribution, and the cases of human immunodeficiency virus/acquired immunodeficiency syndrome cases with social determinants of health.

Methods: Ecological and analytical study, carried out based on the cases of human immunodeficiency virus/acquired immunodeficiency syndrome notified in a state in the Brazilian Midwest, from 2009 to 2018. The study used descriptive analysis, polynomial regression, and geospatial analysis.

Clinical-Epidemiological Characteristics and Mortality in Patients with Sickle Cell Anemia: A Retrospective Cohort Study of 1980 at 2018.

Purpose: To analyze the clinical-epidemiological characteristics and mortality in patients with sickle-cell anemia (SCA).

Patients And Methods: A cohort study with retrospective data, conducted in two reference hospitals for SCA treatment from January 1980 to December 2018, recorded in two reference services. With a 5% significance level, the Chi-Square and Student's t-tests were employed in the inferential statistical analysis.

Extrication techniques of entrapped car crash victims: a scoping review.

Objective: to summarize the extrication techniques of entrapped car crash victims with potential spinal injury.

Method: a literature review study, of scoping review type, using the MEDLINE/PubMed, CINAHL, Scopus, Science Direct, Web of Science, Cochrane Library and gray literature data sources, without time frame, with studies that addressed extricating techniques extrication of entrapped car crash victims.

Results: a total of 33 studies were included that enabled identifying and summarizing the different types of extrication and respective devices for extrication of entrapped car crash victims, indicated according to injury assessment and the victim's clinical condition.

Impact of sterile gloves on blood-culture contamination rates: A randomized clinical trial.

Background: Reducing the blood-culture contamination rate is a constant challenge for health services. This study aimed to analyze whether blood-culture (BC) collection using sterile gloves reduces the contamination rate when compared to the non-sterile gloves, and to compare baseline and intervention periods.

Methods: A randomized clinical trial, performed in an intensive care unit in Brazil and paired in two groups: sterile (BCs obtained with modified sterile technique: only sterile gloves; no fenestrated drape or dedicated sterile collection kit) and clean (clean technique: usual care with non-sterile gloves).

Cornea donation process and tissue quality for transplantation.

Introduction: The quality of the corneal tissue can be influenced by several factors inherent to the recipient, donor, and to the donation and transplantation process. The donated corneal tissue can be classified by its quality as excellent, good, regular, bad, or unacceptable for transplantation, evaluating it in a slit lamp.

Objective: To analyze the relationship between the clinical and sociodemographic variables of the donors and the donation process and the classification of the quality of the corneal tissue collected for transplantation.

Design, synthesis and antihypertensive evaluation of novel codrugs with combined angiotensin type 1 receptor antagonism and neprilysin inhibition.

The multifactorial etiology of hypertension has promoted the research of blood pressure-lowering agents with multitarget actions to achieve better clinical outcomes. We describe here the discovery of novel dual-acting antihypertensive codrugs combining pharmacophores with angiotensin type 1 (AT1) receptor antagonism and neprilysin (NEP) inhibition. Specifically, the codrugs combine the AT1 antagonists losartan or its carboxylic acid active metabolite (E-3174) with selected monocarboxylic acid NEP inhibitors through a cleavable linker.

Coping strategies of family members of intensive care unit patients.

Objective: To analyse the coping strategies of family members of patients admitted to intensive care units.

Design: A cross-sectional study developed with 70 relatives of patients admitted to the intensive care unit.

Setting: An adult intensive care unit at a university hospital in Brazil.

Physical violence and verbal abuse against nurses working with risk stratification: characteristics, related factors, and consequences.

Objective: to analyze the characteristics, related factors, and consequences of physical violence and verbal abuse against nurses working with risk stratification.

Methods: a cross-sectional, descriptive and quantitative study carried out with 80 nurses who work with risk stratification in emergency services. Data were collected using an adapted instrument and analyzed using (uni)bivariate inferential statistics.

Effectiveness of clinical surface cleaning and disinfection: evaluation methods.

Objective: To discuss the methods employed to evaluate the effectiveness of clinical surface cleaning and disinfection (C&D).

Method: This is a theoretical reflection based on scientific studies and the experience of the authors. Knowledge and current gaps, the need for further studies, and practical application of the methods were approached.

Critical thinking in nursing students from two Brazilian regions.

Objective: To analyze the overall critical thinking and the development of each of the cognitive skills or attributes that compose it in students of the undergraduate program in nursing through the creation of concept maps in two Brazilian teaching institutions.

Method: Before-and-after experimental study, randomized, performed in two universities of two Brazilian regions, with a sample of 21 subjects at the A school and 56 at the B school. Data were collected through sociodemographic questionnaire and the California Critical Thinking Skills Test.

Syphilis Notifications and the Triggering Processes for Vertical Transmission: A Cross-Sectional Study.

Syphilis is a disease that is found all over the world that causes damaging effects to the fetus through vertical transmission. This study aimed to analyze the processes that trigger the vertical transmission of syphilis through gestational and congenital syphilis notifications. It is a cross-sectional study.