Publications by authors named "Marco Summa"
Article Synopsis
- - This study assessed whether radiomic features from pretreatment [F]FDG PET scans could better predict tumor response and survival in patients with locally advanced cervical cancer after chemoradiotherapy and surgery compared to traditional PET measurements and histopathologic data.
- - Out of 195 patients analyzed, 67.2% showed no or minimal residual tumors after treatment, while 32.8% had larger residual tumors; further follow-ups indicated a 31.3% recurrence or progression rate, with 20% mortality due to the disease.
- - Although some conventional and radiomic features were found to differ between responders and nonresponders, the predictive power for survival and response was generally low, with most metrics yielding areas under the curve
Purpose: Radioguided surgery (RGS) is a technique that helps the surgeon to achieve a tumour resection as complete as possible, by means of the intraoperative detection of particles emitted by a radiotracer that bounds to tumoural cells. This study aimed to investigate the applicability of β-RGS for tumour resection and margin assessment in cervical cancer patients preoperatively injected with [F]FDG, by means of Monte Carlo simulations.
Methods: Patients were retrospectively included if they had a recurrent or persistent cervical cancer, underwent preoperative PET/CT to exclude distant metastases and received radical surgery.
This study investigated the predictive role of baseline F-FDG PET/CT (bPET/CT) radiomics from two distinct target lesions in patients with classical Hodgkin's lymphoma (cHL). cHL patients examined with bPET/CT and interim PET/CT between 2010 and 2019 were retrospectively included. Two bPET/CT target lesions were selected for radiomic feature extraction: Lesion_A, with the largest axial diameter, and Lesion_B, with the highest SUV.
View Article and Find Full Text PDFAim: The aim of this study is to assess whether there are some correlations between radiomics and baseline clinical-biological data of prostate cancer (PC) patients using Fluorine-18 Fluoroethylcholine (F-FECh) PET/CT.
Methods: Digital rectal examination results (DRE), Prostate-Specific Antigen (PSA) serum levels, and bioptical-Gleason Score (GS) were retrospectively collected in newly diagnosed PC patients and considered as outcomes of PC. Thereafter, Volumes of interest (VOI) encompassing the prostate of each patient were drawn to extract conventional and radiomic PET features.
Article Synopsis
- Family history of thyroid cancer is linked to a higher risk of extrathyroidal extension (ETE) and multifocality in thyroid malignancies, prompting some experts to recommend more aggressive surgical techniques.* -
- This study aimed to determine if neck ultrasonography could effectively identify or rule out multifocality and ETE in patients with a first-degree relative who had thyroid cancer.* -
- Results showed that while ultrasonography has some predictive value for multifocality and ETE, it is not reliable enough to exclude these features before surgery, suggesting that negative ultrasound findings do not guarantee the absence of these complications.*
There is controversy in the literature regarding a distinct subset of thyroid carcinoma whose histologically classification falls between well-differentiated and anaplastic carcinomas, previously identified as 'poorly differentiated thyroid carcinoma' (PDTC), or 'insular carcinoma', in view of the peculiar morphological characteristics of the cell groupings. The correct diagnosis and treatment of this entity have important prognostic and therapeutic significance. In this review, we describe the epidemiology, diagnosis, and management of PDTC and report our single centre experience to add to the limited evidence existing in the literature.
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