Publications by authors named "Marco Roscio"
Background And Objectives: Patients with pediatric-onset multiple sclerosis (MS) can be especially vulnerable to cognitive impairment (CI) due to the onset of MS during a critical period for CNS development and maturation. The objective of this longitudinal study was to assess long-term cognitive functioning and socioprofessional attainment in the Italian pediatric MS cohort, previously assessed at baseline and 2 and 5 years.
Methods: The 48 patients evaluated at the 5-year assessment were screened for inclusion.
Importance: Cognitive impairment is a common and disabling feature of multiple sclerosis (MS), but a precise characterization of cognitive phenotypes in patients with MS is lacking.
Objectives: To identify cognitive phenotypes in a clinical cohort of patients with MS and to characterize their clinical and magnetic resonance imaging (MRI) features.
Design, Setting, And Participants: This multicenter cross-sectional study consecutively screened clinically stable patients with MS and healthy control individuals at 8 MS centers in Italy from January 1, 2010, to October 31, 2019.
The above article was published online with an error in author name's affiliation. The Author Claudia Niccolai has changed her affiliation to IRCCS Fondazione Don Carlo Gnocchi, Florence, Italy.
View Article and Find Full Text PDFBackground: The increase in life expectancy of patients with multiple sclerosis (MS) requires a better knowledge of disease features in the older patients group.
Objective: To describe the prevalence and profile of cognitive impairment (CI) in older patients with MS and perform a comparison with younger patients.
Methods: Patients were consecutively recruited for 6 months.
Background: Patients with paediatric-onset multiple sclerosis (POMS) could be at an increased risk for cognitive impairment (CI), given the potential harmful effects of disease activity in neurodevelopment. However, there is scarce information on their long-term cognitive outcomes.
Objective: To compare the prevalence and profile of CI between adults with a history of POMS and those with classic, adult-onset multiple sclerosis (AOMS).
Background: There is limited and inconsistent information on the clinical determinants of cognitive impairment (CI) in multiple sclerosis (MS).
Objective: The aim of this study was to compare the prevalence and profile of CI across MS disease subtypes and assess its clinical determinants.
Methods: Cognitive performance was assessed through the Brief Repeatable Battery and the Stroop test in consecutive patients with MS referred to six Italian centers.
Cognitive rehabilitation in multiple sclerosis (MS) has been reported to induce neuropsychological improvements, but the persistence of these effects has been scarcely investigated over long follow ups. Here, the results of a multicenter randomized clinical trial are reported, in which the efficacy of 15 week domain specific cognitive training was evaluated at 2 years follow up in 41 patients. Included patients were randomly assigned either to domain specific cognitive rehabilitation, or to aspecific psychological intervention.
View Article and Find Full Text PDFBackground: The study of cognitive reserve (CR) in relationship with cognitive impairment (CI) in pediatric-onset multiple sclerosis (POMS) may provide cues to identifying subjects at higher risk of impairment and scope for therapeutic strategies.
Objectives: To assess the potential impact of CR on cognition in a cohort of POMS patients.
Methods: In all, 48 POMS patients were followed up for 4.
Article Synopsis
- A new cognitive assessment tool called BICAMS was developed for evaluating cognitive impairment in multiple sclerosis (MS) patients, aiming to be simple for clinical use.
- The study involved 192 MS patients comparing their performances on BICAMS and the Brief Repeatable Battery (BRB), with a significant focus on identifying cognitive impairment based on established scoring criteria.
- Results showed moderate agreement between the two assessment tools, indicating that BICAMS is a viable option for clinical practice, especially when specific tests like the SDMT are included in the evaluation.
Objective: The aim of the study was to perform a third cognitive assessment in our pediatric-onset multiple sclerosis (MS) patient cohort and determine predictors of the individual cognitive outcome.
Methods: After 4.7 ± 0.