Publications by authors named "Marco Peradotto"
Article Synopsis
- Streptococcus pneumoniae
- in Piedmont, Italy.
- * Data from 2008 to present showed that out of 2,076 strains collected, 21.9% were resistant to penicillin G and 40.3% to erythromycin, with an overall increased risk of penicillin-resistant infections across all age groups.
- * The findings indicate a significant rise in penicillin G-resistant pneumococcal disease particularly among infants and the elderly following vaccination implementation, while the SARS-CoV2 pandemic didn't show a significant impact on AMR
Background: Fosfomycin is an old bactericidal drug that has gained increasing interest in the last decade for its potential use in multi-drug resistant gram-negative infections. However, evidence on fosfomycin susceptibility testing reports a poor correlation between commercial methods vs. reference agar dilution (AD) for (EB).
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- - The lack of a globally accepted breakpoint and reliable susceptibility testing methods limits the effectiveness of fosfomycin against certain bacterial infections.
- - A study compared three testing methods (disk diffusion, E-test, and automated broth microdilution) to the reference method (agar dilution) using 150 isolates, revealing varying levels of agreement and error rates among methods.
- - Disk diffusion and E-test showed better categorical agreement for higher concentrations of fosfomycin, while automated broth microdilution had the lowest error rate but overall poor agreement, indicating the need for more extensive research and definitive breakpoints for fosfomycin.
Purpose: The impact of SARS-CoV-2 pandemic on other pathogens is largely unknown. We aimed to compare the prevalence of vaccine-preventable invasive bacterial infections before and during the pandemic in Piedmont (Italy).
Methods: We defined the monthly incidence of S.
Article Synopsis
- The study aimed to assess how common ceftazidime/avibactam (CZA) resistance is among specific bacteria (carbapenemase-producing Enterobacterales) found in blood cultures, while also evaluating methods for identifying KPC variants linked to this resistance.
- Researchers tested non-duplicate CPE strains from blood cultures collected between 2018-2020 for their ability to withstand antibiotics and used molecular testing to classify the carbapenemase producers, specifically looking at those with high CZA MIC levels.
- Results showed a notable CZA resistance rate of 13.7%, revealing challenges in detecting certain KPC variants using the evaluated phenotypic methods, suggesting that a combination of
We evaluate the performance of BD Phoenix (BD Diagnostic; Hunt Valley, MD) and MiscroScan WalkAway (Beckman Coulter Inc; Carlsbad, CA) systems versus reference agar dilution method for fosfomycin susceptibility determination in 200 Staphylococcus aureus clinical isolates. Both methods exhibit ≤89.0% of categorica agreement and ≥63.
View Article and Find Full Text PDFWhipworms are responsible for up to 500 million cases of trichuriasis worldwide, with higher endemicity in tropical and sub-tropical countries. In non-endemic countries, trichuriasis can be accidentally diagnosed upon colonoscopy, often in the presence of negative microscopy. Here, we describe an incidental diagnosis of trichuriasis in an HIV patient residing in a non-endemic area (i.
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