Perineural infiltration as a prognostic factor in surgically treated gallbladder cancer A single center experience and literature review.

Introduction: Gallbladder cancer (GBC) is the most incident cancer of the biliary tract with only 5-13% of the sufferers surviving for five years. The aim of this study was to evaluate the prognostic role of perineural invasion (PNI) and its association with several clinicopathological variables in a cohort of surgically treated patients, and through a comprehensive review of the scientific literature.

Materials And Methods: Twenty-five consecutive patients submitted to curative surgery for GBC from 2008 through 2016 were enrolled.