Publications by authors named "Marco Nuno de Canha"

Angiogenesis is an essential mechanism in both physiological and pathological functions, such as wound healing and cancer metastasis. Several growth factors mediate angiogenesis, including vascular endothelial growth factor (VEGF) and platelet derived growth factor (PDGF). This study evaluated the potential wound healing activity of Szyszyl (GR) and its effect on growth factors regulating angiogenesis.

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The human skin is home to millions of bacteria, fungi, and viruses which form part of a unique microbiome. Commensal microbes, including can occasionally become opportunistic resulting in the onset of dermatological diseases such as acne. Acne is defined as a chronic inflammatory disorder based on its ability to persist for long periods throughout an individual's life.

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The Gram-positive bacterium (previously ), plays an important role in the pathogenesis and progression of the dermatological skin disorder acne vulgaris. The methanolic extract of (L.) Sweet (HO-MeOH) was investigated for its ability to target bacterial growth and pathogenic virulence factors associated with acne progression.

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L. subsp. is an endemic species of the Eastern Mediterranean region with several uses in traditional medicine.

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Greyia radlkoferi ethanol extract and its five compounds were tested for their inhibitory activity against the mushroom tyrosinase enzyme and melanin production on melanocytes. The crude extract showed significant tyrosinase inhibition with IC of 17.96μg/ml.

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This study compared different commercially available viability reagents. The growth indicator reagents include p-iodonitrotetrazolium violet (INT), PrestoBlue, and Alamar Blue which were used for antimicrobial analysis against Streptococcus mutans, Prevotella intermedia, Propionibacterium acnes, and Mycobacterium tuberculosis. PrestoBlue and Alamar Blue are resazurin based reagents that resulted in a quick and easily distinguishable colour change that allowed for visual readings.

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