Publications by authors named "Marco Normanno"
Background: Epileptiform activity, including status epilepticus (SE), occurs in up to one-third of comatose survivors of cardiac arrest and may predict poor outcome. The relationship between SE and hypoxic-ischemic brain injury (HIBI) is not established.
Methods: This is a single-center retrospective study on consecutive patients with post-anoxic super-refractory SE.
Background: "Macintosh"-videolaryngoscopes (VLs) are VLs that allow both direct and indirect laryngoscopy for intubation. We describe the decision-making and implementation-processes that our hospital used regarding the choice of device. We compared the performances of 4 Macintosh-VLs both in direct and indirect laryngoscopy.
View Article and Find Full Text PDFObjective: The sex of the patients has been shown to affect postoperative pain and morphine consumption; still a clear understanding able to explain the reasons behind this difference struggles to emerge. Our research aimed to investigate one specific aspect of the variability in morphine consumption between sexes. Previous studies have shown that circadian rhythm can influence opioid consumption.
View Article and Find Full Text PDFArticle Synopsis
- The study investigates how genetic and environmental factors contribute to differences in opioid consumption after surgery, focusing on single nucleotide polymorphisms (SNPs) in specific genes.
- An analysis of 20 SNPs from 201 patients showed that certain combinations of SNPs in the OPRM1, COMT, and ESR1 genes significantly affect morphine consumption and pain levels.
- Results indicate that using a combination of genetic markers could improve understanding of opioid needs and lead to better diagnostic tools for managing pain post-surgery.