Background: The COVID-19 pandemic prompted the scientific community to share timely evidence, also in the form of pre-printed papers, not peer reviewed yet.
Purpose: To develop an artificial intelligence system for the analysis of the scientific literature by leveraging on recent developments in the field of Argument Mining.
Methodology: Scientific quality criteria were borrowed from two selected Cochrane systematic reviews.
The investigation of visual categorization has recently been aided by the introduction of deep convolutional neural networks (CNNs), which achieve unprecedented accuracy in picture classification after extensive training. Even if the architecture of CNNs is inspired by the organization of the visual brain, the similarity between CNN and human visual processing remains unclear. Here, we investigated this issue by engaging humans and CNNs in a two-class visual categorization task.
View Article and Find Full Text PDFAttention is an increasingly popular mechanism used in a wide range of neural architectures. The mechanism itself has been realized in a variety of formats. However, because of the fast-paced advances in this domain, a systematic overview of attention is still missing.
View Article and Find Full Text PDFDeep learning is bringing remarkable contributions to the field of argumentation mining, but the existing approaches still need to fill the gap toward performing advanced reasoning tasks. In this position paper, we posit that neural-symbolic and statistical relational learning could play a crucial role in the integration of symbolic and sub-symbolic methods to achieve this goal.
View Article and Find Full Text PDFComput Methods Programs Biomed
March 2020
Background And Objectives: Malignant lymphomas are cancers of the immune system and are characterized by enlarged lymph nodes that typically spread across many different sites. Many different histological subtypes exist, whose diagnosis is typically based on sampling (biopsy) of a single tumor site, whereas total body examinations with computed tomography and positron emission tomography, though not diagnostic, are able to provide a comprehensive picture of the patient. In this work, we exploit a data-driven approach based on multiple-instance learning algorithms and texture analysis features extracted from positron emission tomography, to predict differential diagnosis of the main malignant lymphomas subtypes.
View Article and Find Full Text PDFUnderstanding and correctly modeling urban mobility is a crucial issue for the development of smart cities. The estimation of individual trips from mobile phone positioning data (i.e.
View Article and Find Full Text PDFIEEE Trans Neural Netw Learn Syst
November 2019
Long short-term memory (LSTM) networks have recently shown remarkable performance in several tasks that are dealing with natural language generation, such as image captioning or poetry composition. Yet, only few works have analyzed text generated by LSTMs in order to quantitatively evaluate to which extent such artificial texts resemble those generated by humans. We compared the statistical structure of LSTM-generated language to that of written natural language, and to those produced by Markov models of various orders.
View Article and Find Full Text PDFOptical chemical structure recognition is the problem of converting a bitmap image containing a chemical structure formula into a standard structured representation of the molecule. We introduce a novel approach to this problem based on the pipelined integration of pattern recognition techniques with probabilistic knowledge representation and reasoning. Basic entities and relations (such as textual elements, points, lines, etc.
View Article and Find Full Text PDFIEEE/ACM Trans Comput Biol Bioinform
April 2014
Prediction of binding sites from sequence can significantly help toward determining the function of uncharacterized proteins on a genomic scale. The task is highly challenging due to the enormous amount of alternative candidate configurations. Previous research has only considered this prediction problem starting from 3D information.
View Article and Find Full Text PDFMetalDetector identifies CYS and HIS involved in transition metal protein binding sites, starting from sequence alone. A major new feature of release 2.0 is the ability to predict which residues are jointly involved in the coordination of the same metal ion.
View Article and Find Full Text PDFHigh-throughput X-ray absorption spectroscopy was used to measure transition metal content based on quantitative detection of X-ray fluorescence signals for 3879 purified proteins from several hundred different protein families generated by the New York SGX Research Center for Structural Genomics. Approximately 9% of the proteins analyzed showed the presence of transition metal atoms (Zn, Cu, Ni, Co, Fe, or Mn) in stoichiometric amounts. The method is highly automated and highly reliable based on comparison of the results to crystal structure data derived from the same protein set.
View Article and Find Full Text PDFMotivation: Accurate prediction of contacts between beta-strand residues can significantly contribute towards ab initio prediction of the 3D structure of many proteins. Contacts in the same protein are highly interdependent. Therefore, significant improvements can be expected by applying statistical relational learners that overcome the usual machine learning assumption that examples are independent and identically distributed.
View Article and Find Full Text PDFUnlabelled: The web server MetalDetector classifies histidine residues in proteins into one of two states (free or metal bound) and cysteines into one of three states (free, metal bound or disulfide bridged). A decision tree integrates predictions from two previously developed methods (DISULFIND and Metal Ligand Predictor). Cross-validated performance assessment indicates that our server predicts disulfide bonding state at 88.
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