Publications by authors named "Marco La Montagna"
Article Synopsis
- - Chronic liver diseases, particularly hepatocellular carcinoma (HCC), exhibit a notable gender disparity, with men showing higher incidence rates than women due to factors like risk distribution.
- - The liver demonstrates sexual dysmorphism, highlighting its sensitivity to sex hormones (androgens and estrogens), which influence the development, aggressiveness, and treatment response of HCC.
- - This review aims to explore the factors contributing to the gender differences in HCC incidence, focusing on the significant role of sex hormones in the disease's pathophysiology.
Despite maximizing techniques and patient selection, liver resection and ablation for HCC are still associated with high rates of recurrence. To date, HCC is the only cancer with no proven adjuvant or neoadjuvant therapy used in association to potentially curative treatment. Perioperative combination treatments are urgently needed to reduce recurrence rates and improve overall survival.
View Article and Find Full Text PDFHepatitis B virus (HBV) is a major cause of chronic hepatitis, liver cirrhosis, and hepatocellular carcinoma. Despite the advent of vaccines and potent antiviral agents able to suppress viral replication, recovery from chronic HBV infection is still an extremely difficult goal to achieve. Complex interactions between virus and host are responsible for HBV persistence and the risk of oncogenesis.
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