Effectiveness and Risk Factors for Virological Outcome of Raltegravir-Based Therapy for Treatment-Experienced HIV-Infected Patients.

Objective: We evaluated the effectiveness of a raltegravir (RAL)-containing regimen plus an optimized background regimen in HIV-1 highly treatment-experienced patients.

Design: A retrospective cohort, multicentre study was conducted.

Methods: Adult (>16 years old) HIV treatment-experience patients starting therapy with a RAL-containing regimen were included.

Effectiveness and risk factors for virological outcome of darunavir-based therapy for treatment-experienced HIV-infected patients.

Objective: We evaluated the effectiveness of darunavir (DRV) treatment plus an optimized background regimen in 120 HIV-1 treatment-experienced patients.

Design: Retrospective cohort, multicenter study.

Methods: Adults >16 years with virological treatment failure starting therapy with a DRV-containing regimen were included.