Publications by authors named "Marco Covani"

Background: Coronary artery calcium score (CACS) is widely used for risk stratification. However, in patients with established coronary artery disease, its clinical implication and relationship with plaque vulnerability are unclear. We sought to correlate the CACS and plaque vulnerability assessed by optical coherence tomography.

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Article Synopsis
  • This study investigated the differences in total plaque burden between patients experiencing plaque rupture versus plaque erosion during acute coronary syndromes, employing coronary computed tomography angiography (CTA) and optical coherence tomography for analysis.
  • A total of 232 patients were examined, revealing that those with plaque rupture showed significantly greater total plaque, non-calcified plaque, low-density non-calcified plaque, and calcified plaque burdens compared to those with plaque erosion.
  • The findings suggest that plaque rupture is associated with more severe coronary artery disease, indicating a potential need for varied clinical management strategies for patients based on the type of plaque pathology present.
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Background: Echocardiography is essential in cardiovascular medicine for screening, diagnosis, and monitoring. Artificial intelligence (AI) has the potential to improve echocardiography by reducing variability and analysis time. While 3D echocardiography is becoming more accurate, 2D imaging still dominates clinical care.

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Background: Transcatheter left atrial appendage occlusion (LAAO) is a valuable therapeutic option for stroke prevention in patients with atrial fibrillation (AF) at high bleeding risk. However, complex LAA anatomies sometimes preclude the adoption of commercially available LAAO devices. The design of a custom-made LAAO device is a promising strategy in these cases.

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Infra-inguinal Chronic Total Occlusions recanalisation is considered technically challenging. The conventional manipulation of standard guidewires and catheters has proven to be successful in a considerable percentage of cases but success rate could dramatically drop in presence of challenging lesions. The additional use of retrograde access and re-entry devices could increase technical success but could negatively affect procedural time and overall costs.

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Objective: The endovascular treatment of femoropopliteal lesions is an integral part of managing peripheral arterial disease. The antegrade approach is the most widely used technique with good evidence for its safety and efficacy. However, crossing a lesion, particularly chronic total occlusions (CTO), can be technically challenging and so the retrograde approach is increasingly used to maximize the chances of procedural success.

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